Jerry E Stewart
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Explore the profile of Jerry E Stewart including associated specialties, affiliations and a list of published articles.
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49
Citations
388
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Recent Articles
1.
Nazam N, Bownes L, Julson J, Quinn C, Erwin M, Marayati R, et al.
Cancers (Basel)
. 2024 Nov;
16(22).
PMID: 39594793
Background: Neuroblastoma (NB) remains one of the deadliest pediatric solid tumors. Recent advancements aimed at improving outcomes have been insufficient, and patients with high-risk NB continue to have a poor...
2.
Nazam N, Erwin M, Julson J, Quinn C, Beierle A, Bownes L, et al.
J Biol Chem
. 2024 Oct;
300(11):107892.
PMID: 39419284
Leptomeningeal dissemination (LMD) is the primary cause of treatment failure in children with group 3 medulloblastoma (MB). Building on our previous work on protein phosphatase 2A (PP2A) activation in MB,...
3.
Quinn C, Julson J, Markert H, Nazam N, Butey S, Stewart J, et al.
Cancer Immunol Immunother
. 2024 Sep;
73(11):221.
PMID: 39235531
Background: Neuroblastoma is the most common extracranial solid tumor in children and accounts for 15% of pediatric cancer related deaths. Targeting neuroblastoma with immunotherapies has proven challenging due to a...
4.
Quinn C, Beierle A, Williams A, Marayati R, Bownes L, Market H, et al.
Transl Oncol
. 2024 Jul;
47:102045.
PMID: 38959709
Background: Pediatric gastroenteropancreatic neuroendocrine tumors are exceedingly rare, resulting in most pediatric treatment recommendations being based on data derived from adults. Trametinib is a kinase inhibitor that targets MEK1/2 and...
5.
Julson J, Quinn C, Nazam N, Bownes L, Stewart J, Beierle E
J Pediatr Surg
. 2024 Apr;
59(7):1334-1341.
PMID: 38570263
Background: Chemoresistance contributes to relapse in high-risk neuroblastoma. Cancer cells acquire resistance through multiple mechanisms, including drug efflux pumps. In neuroblastoma, multidrug resistance-associated protein-1 (MRP1/ABCC1) efflux pump expression correlates with...
6.
Julson J, Quinn C, Butey S, Erwin M, Marayati R, Nazam N, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203596
Hepatoblastoma is the most common primary pediatric liver tumor. Children with pulmonary metastases at diagnosis experience survival rates as low as 25%. We have shown PIM kinases play a role...
7.
Julson J, Horton S, Quinn C, Beierle A, Bownes L, Stewart J, et al.
J Pediatr Surg
. 2023 Nov;
59(3):473-482.
PMID: 37919169
Background: Sarcomas are a heterogenous collection of bone and soft tissue tumors. The heterogeneity of these tumors makes it difficult to standardize treatment. CDK 4/6 inhibitors are a family of...
8.
Quinn C, Beierle A, Julson J, Erwin M, Alrefai H, Markert H, et al.
Int J Bioprint
. 2023 Jun;
9(4):723.
PMID: 37323483
The use of three-dimensional (3D) bioprinting has remained at the forefront of tissue engineering and has recently been employed for generating bioprinted solid tumors to be used as cancer models...
9.
The Effects of Protein Phosphatase 2A Activation with Novel Tricyclic Sulfonamides on Hepatoblastoma
Bownes L, Julson J, Quinn C, Hutchins S, Erwin M, Markert H, et al.
J Pediatr Surg
. 2023 Mar;
58(6):1145-1154.
PMID: 36907775
Background: The tumor suppressor, protein phosphatase 2A (PP2A), is downregulated in hepatoblastoma. We aimed to examine the effects of two novel compounds of the tricyclic sulfonamide class, ATUX-3364 (3364) and...
10.
Julson J, Quinn C, Bownes L, Hutchins S, Stewart J, Aye J, et al.
J Pediatr Surg
. 2023 Mar;
58(6):1155-1163.
PMID: 36907773
Background: Neuroblastoma arises from aberrancies in neural stem cell differentiation. PIM kinases contribute to cancer formation, but their precise role in neuroblastoma tumorigenesis is poorly understood. In the current study,...