Elizabeth A Beierle
Overview
Explore the profile of Elizabeth A Beierle including associated specialties, affiliations and a list of published articles.
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160
Citations
1477
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Recent Articles
1.
Ghufran S, Brown M, Beierle E
Mol Ther Oncol
. 2025 Feb;
33(1):200930.
PMID: 39895692
Cancer is the second leading cause of death in children, and solid tumors make up 30% of childhood cancers. Molecular profiling of pediatric solid tumors allows a personalized approach to...
2.
Nazam N, Bownes L, Julson J, Quinn C, Erwin M, Marayati R, et al.
Cancers (Basel)
. 2024 Nov;
16(22).
PMID: 39594793
Background: Neuroblastoma (NB) remains one of the deadliest pediatric solid tumors. Recent advancements aimed at improving outcomes have been insufficient, and patients with high-risk NB continue to have a poor...
3.
Koenig S, Mathis M, Onwubiko C, Chen M, Beierle E, Russell R
J Pediatr Surg
. 2024 Oct;
60(1):161989.
PMID: 39442328
Background: Burn injuries remain one of the leading causes of injury and death in children. Studies have demonstrated a higher mortality for pediatric burns associated with non-accidental injury. Using data...
4.
Nazam N, Erwin M, Julson J, Quinn C, Beierle A, Bownes L, et al.
J Biol Chem
. 2024 Oct;
300(11):107892.
PMID: 39419284
Leptomeningeal dissemination (LMD) is the primary cause of treatment failure in children with group 3 medulloblastoma (MB). Building on our previous work on protein phosphatase 2A (PP2A) activation in MB,...
5.
Quinn C, Julson J, Markert H, Nazam N, Butey S, Stewart J, et al.
Cancer Immunol Immunother
. 2024 Sep;
73(11):221.
PMID: 39235531
Background: Neuroblastoma is the most common extracranial solid tumor in children and accounts for 15% of pediatric cancer related deaths. Targeting neuroblastoma with immunotherapies has proven challenging due to a...
6.
Jones A, Tuy K, Hawkins C, Quinn C, Saad J, Gary S, et al.
Cancers (Basel)
. 2024 Aug;
16(16).
PMID: 39199623
Glioblastoma (GBM) is an immunologically cold tumor, but several immunotherapy-based strategies show promise, including the administration of ex vivo expanded and activated cytotoxic gamma delta T cells. Cytotoxicity is partially...
7.
Koenig S, Deng L, Onwubiko C, Beierle E, Russell R
J Surg Res
. 2024 Aug;
301:584-590.
PMID: 39089134
Introduction: Burn injuries are among the top ten leading causes of unintentional death in pediatric patients and are encountered by pediatric surgeons in all practice settings. There is a lack...
8.
Quinn C, Beierle A, Williams A, Marayati R, Bownes L, Market H, et al.
Transl Oncol
. 2024 Jul;
47:102045.
PMID: 38959709
Background: Pediatric gastroenteropancreatic neuroendocrine tumors are exceedingly rare, resulting in most pediatric treatment recommendations being based on data derived from adults. Trametinib is a kinase inhibitor that targets MEK1/2 and...
9.
Six K, Aban I, Daniels G, Wolfson J, Beierle E, Kutny M, et al.
J Pediatr Hematol Oncol
. 2024 Apr;
46(6):322-326.
PMID: 38652051
Lymphadenopathy is a common reason for referral to a subspecialist, which may result in significant anxiety for parents. Understanding which patients require a subspecialty referral for lymphadenopathy is key to...
10.
Julson J, Quinn C, Nazam N, Bownes L, Stewart J, Beierle E
J Pediatr Surg
. 2024 Apr;
59(7):1334-1341.
PMID: 38570263
Background: Chemoresistance contributes to relapse in high-risk neuroblastoma. Cancer cells acquire resistance through multiple mechanisms, including drug efflux pumps. In neuroblastoma, multidrug resistance-associated protein-1 (MRP1/ABCC1) efflux pump expression correlates with...