Jerry Donovan
Overview
Explore the profile of Jerry Donovan including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
3428
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0
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Recent Articles
1.
Bhutani K, Stansifer K, Ticau S, Bojic L, Villani A, Slisz J, et al.
Science
. 2021 Jan;
371(6533).
PMID: 33446482
Sperm are haploid but must be functionally equivalent to distribute alleles equally among progeny. Accordingly, gene products are shared through spermatid cytoplasmic bridges that erase phenotypic differences between individual haploid...
2.
Wylie A, Schoepfer J, Jahnke W, Cowan-Jacob S, Loo A, Furet P, et al.
Nature
. 2017 Mar;
543(7647):733-737.
PMID: 28329763
Chronic myeloid leukaemia (CML) is driven by the activity of the BCR-ABL1 fusion oncoprotein. ABL1 kinase inhibitors have improved the clinical outcomes for patients with CML, with over 80% of...
3.
Beroukhim R, Mermel C, Porter D, Wei G, Raychaudhuri S, Donovan J, et al.
Nature
. 2010 Feb;
463(7283):899-905.
PMID: 20164920
A powerful way to discover key genes with causal roles in oncogenesis is to identify genomic regions that undergo frequent alteration in human cancers. Here we present high-resolution analyses of...
4.
Gaither A, Porter D, Yao Y, Borawski J, Yang G, Donovan J, et al.
Cancer Res
. 2007 Dec;
67(24):11493-8.
PMID: 18089776
Smac mimetic compounds targeting the inhibitor of apoptosis proteins (IAP) baculoviral IAP repeat-3 domain are presumed to reduce the threshold for apoptotic cell death by alleviating caspase-9 repression. We explored...
5.
Puigserver P, Rhee J, Donovan J, Walkey C, Yoon J, Oriente F, et al.
Nature
. 2003 May;
423(6939):550-5.
PMID: 12754525
Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately activated in diabetes mellitus. Glucocorticoids and glucagon have strong gluconeogenic actions on the liver. In...
6.
Lin J, Puigserver P, Donovan J, Tarr P, Spiegelman B
J Biol Chem
. 2001 Dec;
277(3):1645-8.
PMID: 11733490
Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) plays a critical role in regulating multiple aspects of energy metabolism, including adaptive thermogenesis, mitochondrial biogenesis, and fatty acid beta-oxidation. Recently, this coactivator of...