Jerome G Chandraseelan
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Explore the profile of Jerome G Chandraseelan including associated specialties, affiliations and a list of published articles.
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7
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57
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Recent Articles
1.
Palanivel S, Zhurina A, Doan P, Chandraseelan J, Khandelwal V, Zubkov F, et al.
Saudi Pharm J
. 2018 Mar;
26(3):430-436.
PMID: 29556135
Arylhydrazones of active methylene compounds (AHAMCs) are potent chemotherapy agents for the cancer treatment. AHAMCs enhance the apoptotic cell death and antiproliferation properties in cancer cells. In this study, a...
2.
Karjalainen A, Doan P, Chandraseelan J, Sandberg O, Yli-Harja O, Candeias N, et al.
Anticancer Agents Med Chem
. 2017 Mar;
17(12):1710-1720.
PMID: 28356015
Background: Phenolic compounds are known for their cytotoxic properties against cancer cells despite their still unclear general mechanism of action. Herein is reported the evaluation of the cytotoxic effects of...
3.
Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines
Doan P, Karjalainen A, Chandraseelan J, Sandberg O, Yli-Harja O, Rosholm T, et al.
Eur J Med Chem
. 2016 May;
120:296-303.
PMID: 27214140
Development of novel anticancer drugs is inevitable to improve treatment of cancers. In this study, novel derivatives of indoline and morpholine were synthesized and tested for their cytotoxic effects on...
4.
Lloyd-Price J, Startceva S, Kandavalli V, Chandraseelan J, Goncalves N, Oliveira S, et al.
DNA Res
. 2016 Mar;
23(3):203-14.
PMID: 27026687
We investigate the hypothesis that, in Escherichia coli, while the concentration of RNA polymerases differs in different growth conditions, the fraction of RNA polymerases free for transcription remains approximately constant...
5.
Oliveira S, Chandraseelan J, Hakkinen A, Goncalves N, Yli-Harja O, Startceva S, et al.
Mol Biosyst
. 2015 Apr;
11(7):1939-45.
PMID: 25923804
Synthetic genetic clocks, such as the Elowitz-Leibler repressilator, will be key regulatory components of future synthetic circuits. We constructed a single-copy repressilator (SCR) by implementing the original repressilator circuit on...
6.
Chandraseelan J, Oliveira S, Hakkinen A, Tran H, Potapov I, Sala A, et al.
Mol Biosyst
. 2013 Oct;
9(12):3117-23.
PMID: 24104727
We studied the behaviour of the repressilator at 28 °C, 30 °C, 33 °C, and 37 °C. From the fluorescence in each cell over time, we determined the period of...
7.
Makela J, Kandhavelu M, Oliveira S, Chandraseelan J, Lloyd-Price J, Peltonen J, et al.
Nucleic Acids Res
. 2013 May;
41(13):6544-52.
PMID: 23644285
Using a single-RNA detection technique in live Escherichia coli cells, we measure, for each cell, the waiting time for the production of the first RNA under the control of PBAD...