Jeroen Pouwels
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Explore the profile of Jeroen Pouwels including associated specialties, affiliations and a list of published articles.
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31
Citations
660
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Recent Articles
21.
Pouwels J, Nevo J, Pellinen T, Ylanne J, Ivaska J
J Cell Sci
. 2012 Jul;
125(Pt 14):3271-80.
PMID: 22822081
Integrins are heterodimeric transmembrane adhesion receptors composed of α- and β-subunits. They are ubiquitously expressed and have key roles in a number of important biological processes, such as development, maintenance...
22.
Salmela A, Pouwels J, Kukkonen-Macchi A, Waris S, Toivonen P, Jaakkola K, et al.
Exp Cell Res
. 2012 Jan;
318(5):578-92.
PMID: 22227008
The spindle assembly checkpoint (SAC) is a conserved mechanism that ensures the fidelity of chromosome distribution in mitosis by preventing anaphase onset until the correct bipolar microtubule-kinetochore attachments are formed....
23.
Rantala J, Pouwels J, Pellinen T, Veltel S, Laasola P, Mattila E, et al.
Nat Cell Biol
. 2011 Sep;
13(11):1315-24.
PMID: 21947080
Regulated activation of integrins is critical for cell adhesion, motility and tissue homeostasis. Talin and kindlins activate β1-integrins, but the counteracting inhibiting mechanisms are poorly defined. We identified SHARPIN as...
24.
Kukkonen-Macchi A, Sicora O, Kaczynska K, Oetken-Lindholm C, Pouwels J, Laine L, et al.
J Cell Sci
. 2010 Dec;
124(Pt 2):216-27.
PMID: 21172807
The p38 mitogen-activated protein kinase (p38 MAPK) family, which is comprised of four protein isoforms, p38α, p38β, p38γ and p38δ, forms one of the key MAPK pathways. The p38 MAPKs...
25.
Niittymaki I, Gylfe A, Laine L, Laakso M, Lehtonen H, Kondelin J, et al.
Carcinogenesis
. 2010 Dec;
32(3):305-11.
PMID: 21163887
Frameshift mutations frequently accumulate in microsatellite-unstable colorectal cancers (MSI CRCs) typically leading to downregulation of the target genes due to nonsense-mediated messenger RNA decay. However, frameshift mutations that occur in...
26.
Vuoriluoto M, Laine L, Saviranta P, Pouwels J, Kallio M
Mol Oncol
. 2010 Nov;
5(1):105-11.
PMID: 21051298
Cell division is orchestrated by a complex protein network that aims to maintenance of genomic stability. Visualisation of mitotic protein-protein associations in space and time has been limited due to...
27.
Pouwels J, Carette J, van Lent J, Wellink J
Mol Plant Pathol
. 2010 Jun;
3(6):411-8.
PMID: 20569348
SUMMARY Taxonomy: Cowpea mosaic virus (CPMV) is the type member of the Comoviridae and bears a strong resemblance to animal picornaviruses, both in gene organization and in the amino acid...
28.
Salmela A, Pouwels J, Varis A, Kukkonen A, Toivonen P, Halonen P, et al.
Carcinogenesis
. 2009 Apr;
30(6):1032-40.
PMID: 19395653
Fisetin is a natural flavonol present in edible vegetables, fruits and wine at 2-160 microg/g concentrations and an ingredient in nutritional supplements with much higher concentrations. The compound has been...
29.
Ahonen L, Kukkonen A, Pouwels J, Bolton M, Jingle C, Stukenberg P, et al.
Chromosoma
. 2008 Sep;
118(1):71-84.
PMID: 18784935
Incenp is an essential mitotic protein that, together with Aurora B, Survivin, and Borealin, forms the core of the chromosomal passenger protein complex (CPC). The CPC regulates various mitotic processes...
30.
Pouwels J, Kukkonen A, Lan W, Daum J, Gorbsky G, Stukenberg T, et al.
Cell Cycle
. 2007 Jul;
6(13):1579-85.
PMID: 17617734
Physical connection between the sister chromatids is mediated by the cohesin protein complex. During prophase, cohesin is removed from the chromosome arms while the centromeres remain united. Shugoshin1 (Sgo1) is...