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Jeremy Thorner

Explore the profile of Jeremy Thorner including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 6951
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Recent Articles
1.
Bardwell L, Thorner J
Enzymes . 2023 Nov; 54:137-170. PMID: 37945169
Discovery of the class of protein kinase now dubbed a mitogen (or messenger)-activated protein kinase (MAPK) is an illustrative example of how disparate lines of investigation can converge and reveal...
2.
Emmerstorfer-Augustin A, Thorner J
Annu Rev Cell Dev Biol . 2023 Jun; 39:363-389. PMID: 37339679
Every eukaryotic cell contains two distinct multisubunit protein kinase complexes that each contain a TOR (target of rapamycin) protein as the catalytic subunit. These ensembles, designated TORC1 and TORC2, serve...
3.
Thorner J
Biochem J . 2022 Sep; 479(18):1917-1940. PMID: 36149412
As first demonstrated in budding yeast (Saccharomyces cerevisiae), all eukaryotic cells contain two, distinct multi-component protein kinase complexes that each harbor the TOR (Target Of Rapamycin) polypeptide as the catalytic...
4.
Marshall M, Emmerstorfer-Augustin A, Leskoske K, Zhang L, Li B, Thorner J
Mol Biol Cell . 2022 Sep; 33(12):cor4. PMID: 36137247
No abstract available.
5.
Patterson J, Goupil L, Thorner J
Biomolecules . 2021 Oct; 11(10). PMID: 34680163
Eukaryotes utilize distinct mitogen/messenger-activated protein kinase (MAPK) pathways to evoke appropriate responses when confronted with different stimuli. In yeast, hyperosmotic stress activates MAPK Hog1, whereas mating pheromones activate MAPK Fus3...
6.
Galez H, Roelants F, Palm S, Reynaud K, Ingolia N, Thorner J
Membranes (Basel) . 2021 Jul; 11(7). PMID: 34209236
Members of the Puf family of RNA-binding proteins typically associate via their homology domain with specific short motifs in the 3'-UTR of an mRNA and thereby influence the stability, localization...
7.
Takagi J, Cho C, Duvalyan A, Yan Y, Halloran M, Hanson-Smith V, et al.
G3 (Bethesda) . 2021 Feb; 11(1). PMID: 33561226
Septins are GTP-binding proteins conserved across metazoans. They can polymerize into extended filaments and, hence, are considered a component of the cytoskeleton. The number of individual septins varies across the...
8.
Topolska M, Roelants F, Si E, Thorner J
Biomolecules . 2020 Dec; 10(12). PMID: 33255682
Membrane-tethered sterol-binding Lam/Ltc proteins localize at junctions between the endoplasmic reticulum (ER) membrane and other organelles. Two of the six family members-Lam2/Ltc4 (initially Ysp2) and paralog Lam4/Ltc3-localize to ER-plasma membrane...
9.
Ablasser A, Thorner J
Curr Opin Cell Biol . 2020 Apr; 63:iii-v. PMID: 32278627
No abstract available.
10.
McMurray M, Thorner J
Cytoskeleton (Hoboken) . 2019 Oct; 76(9-10):449-456. PMID: 31614074
Septin family proteins are quite similar to each other both within and between eukaryotic species. Typically, multiple discrete septins co-assemble into linear heterooligomers (usually hexameric or octameric rods) with a...