Jeremy Thompson
Overview
Explore the profile of Jeremy Thompson including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
698
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Recent Articles
1.
Chen Q, Thompson J, Hu Y, Wang H, Slotabec L, Nguyen J, et al.
J Pharmacol Exp Ther
. 2025 Feb;
392(3):100529.
PMID: 39969273
Acute, high-dose metformin (MET, 2 mM) results in partial complex I inhibition in ischemia (ISC)-modified mitochondria. Mitochondrial permeability transition pore (MPTP) opening increases cardiac injury during ISC-reperfusion (REP). We evaluated...
2.
Yakhnitsa V, Thompson J, Ponomareva O, Ji G, Kiritoshi T, Mahimainathan L, et al.
Cells
. 2024 Jun;
13(12.
PMID: 38920682
Neuroplasticity in the amygdala and its central nucleus (CeA) is linked to pain modulation and pain behaviors, but cellular mechanisms are not well understood. Here, we addressed the role of...
3.
Kovilakath A, Mauro A, Valentine Y, Raucci F, Jamil M, Carter C, et al.
Circulation
. 2024 Apr;
150(8):622-641.
PMID: 38660786
Background: Dysregulated metabolism of bioactive sphingolipids, including ceramides and sphingosine-1-phosphate, has been implicated in cardiovascular disease, although the specific species, disease contexts, and cellular roles are not completely understood. Sphingolipids...
4.
Chen Q, Li L, Samidurai A, Thompson J, Hu Y, Willard B, et al.
FASEB J
. 2024 Jan;
38(2):e23404.
PMID: 38197290
The induction of acute endoplasmic reticulum (ER) stress damages the electron transport chain (ETC) in cardiac mitochondria. Activation of mitochondria-localized calpain 1 (CPN1) and calpain 2 (CPN2) impairs the ETC...
5.
Chen Q, Thompson J, Hu Y, Lesnefsky E
Am J Physiol Heart Circ Physiol
. 2023 Dec;
326(2):H385-H395.
PMID: 38099846
Mitochondrial function in aged hearts is impaired, and studies of isolated mitochondria are commonly used to assess their function. The two populations of cardiac mitochondria, subsarcolemmal mitochondria (SSM) and interfibrillar...
6.
Chen Q, Thompson J, Hu Y, Lesnefsky E
Mech Ageing Dev
. 2023 Sep;
215:111859.
PMID: 37661065
Aging-related cardiovascular disease is influenced by multiple factors, with oxidative stress being a key contributor. Aging-induced endoplasmic reticulum (ER) stress exacerbates oxidative stress by impairing mitochondrial function. Furthermore, a decline...
7.
Chen Q, Kovilakath A, Allegood J, Thompson J, Hu Y, Cowart L, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2023 Jul;
1868(10):159366.
PMID: 37473835
The endoplasmic reticulum (ER) plays a key role in the regulation of protein folding, lipid synthesis, calcium homeostasis, and serves as a primary site of sphingolipid biosynthesis. ER stress (ER...
8.
Chen Q, Thompson J, Hu Y, Lesnefsky E
Life (Basel)
. 2022 Aug;
12(8).
PMID: 36013387
Background: Induction of acute ER (endoplasmic reticulum) stress using thapsigargin contributes to complex I damage in mouse hearts. Thapsigargin impairs complex I by increasing mitochondrial calcium through inhibition of Ca-ATPase...
9.
LeBlanc Z, Gauthier M, Lelwala R, Elliott C, McMaster C, Eichner R, et al.
Arch Virol
. 2022 May;
167(8):1701-1705.
PMID: 35579714
Here, we describe the full-length genome sequence of a novel potyvirus, tentatively named "Miscanthus sinensis mosaic virus" (MsiMV), isolated from Miscanthus sinensis (silver grass) held in a post-entry quarantine facility...
10.
Chen Q, Thompson J, Hu Y, Lesnefsky E
Biochem Biophys Res Commun
. 2022 May;
613:127-132.
PMID: 35550199
Activation of calpain1 (CPN1) contributes to mitochondrial dysfunction during cardiac ischemia (ISC) - reperfusion (REP). Blockade of electron transport using amobarbital (AMO) protects mitochondria during ISC-REP, indicating that the electron...