Jeremy S Coleman
Overview
Explore the profile of Jeremy S Coleman including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
37
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Recent Articles
1.
Abe M, Coleman J, Presley C, Schley N, Lindsley C
J Org Chem
. 2024 Feb;
89(5):3500-3508.
PMID: 38340064
Sp-enriched small molecules play a critical role in developing drug candidates. While designing analogues with greater sp character, a methodology utilizing a less explored cyclic-aziridine amide ring-opening reaction to generate...
2.
Gobert A, Smith T, Latour Y, Asim M, Barry D, Allaman M, et al.
Gastroenterology
. 2023 Jun;
165(3):656-669.e8.
PMID: 37271289
Background & Aims: The amino acid hypusine, synthesized from the polyamine spermidine by the enzyme deoxyhypusine synthase (DHPS), is essential for the activity of eukaryotic translation initiation factor 5A (EIF5A)....
3.
Brice-Tutt A, Wilson L, Eans S, Stacy H, Simons C, Simpson G, et al.
Br J Pharmacol
. 2020 Jun;
177(18):4209-4222.
PMID: 32562259
Background And Purpose: The macrocyclic tetrapeptide natural product CJ-15,208 (cyclo[Phe-d-Pro-Phe-Trp]) is a multifunctional μ-opioid receptor and κ-opioid receptor agonist and κ-opioid receptor antagonist that produces antinociception and prevents stress-induced reinstatement...
4.
Ferracane M, Brice-Tutt A, Coleman J, Simpson G, Wilson L, Eans S, et al.
ACS Chem Neurosci
. 2020 Apr;
11(9):1324-1336.
PMID: 32251585
Substance abuse remains a serious public health crisis, affecting millions of people worldwide. Macrocyclic tetrapeptides like CJ-15,208 and [d-Trp]CJ-15,208 demonstrate opioid activity shown to attenuate the rewarding effects of cocaine...