Jeremy Muhlich
Overview
Explore the profile of Jeremy Muhlich including associated specialties, affiliations and a list of published articles.
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15
Citations
313
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Recent Articles
1.
Prabhakaran S, Yapp C, Baker G, Beyer J, Chang Y, Creason A, et al.
Mol Oncol
. 2025 Feb;
PMID: 39927650
The National Cancer Institute (NCI) supports numerous research consortia that rely on imaging technologies to study cancerous tissues. To foster collaboration and innovation in this field, the Image Analysis Working...
2.
Kader T, Lin J, Hug C, Coy S, Chen Y, de Bruijn I, et al.
bioRxiv
. 2024 Oct;
PMID: 39386723
High-Grade Serous Ovarian Cancer (HGSOC) originates from fallopian tube (FT) precursors. However, the molecular changes that occur as precancerous lesions progress to HGSOC are not well understood. To address this,...
3.
Wala J, de Bruijn I, Coy S, Gagne A, Chan S, Chen Y, et al.
bioRxiv
. 2024 Oct;
PMID: 39386479
Significance: pMMR tumors with high T cell infiltration and active immunosuppression are identifiable with a mid-plex imaging assay whose clinical deployment might double the number of treatment-naïve CRCs eligible for...
4.
de Bruijn I, Nikolov M, Lau C, Clayton A, Gibbs D, Mitraka E, et al.
bioRxiv
. 2024 Jul;
PMID: 38979389
The Data Coordinating Center (DCC) of the Human Tumor Atlas Network (HTAN) has played a crucial role in enabling the broad sharing and effective utilization of HTAN data within the...
5.
Warchol S, Troidl J, Muhlich J, Krueger R, Hoffer J, Lin T, et al.
bioRxiv
. 2024 Apr;
PMID: 38659870
Over the past century, multichannel fluorescence imaging has been pivotal in myriad scientific breakthroughs by enabling the spatial visualization of proteins within a biological sample. With the shift to digital...
6.
Prabhakaran S, Yapp C, Baker G, Beyer J, Chang Y, Creason A, et al.
bioRxiv
. 2023 Aug;
PMID: 37547011
The National Cancer Institute (NCI) supports many research programs and consortia, many of which use imaging as a major modality for characterizing cancerous tissue. A trans-consortia Image Analysis Working Group...
7.
Mechanistic model of MAPK signaling reveals how allostery and rewiring contribute to drug resistance
Frohlich F, Gerosa L, Muhlich J, Sorger P
Mol Syst Biol
. 2023 Jan;
19(2):e10988.
PMID: 36700386
BRAF is prototypical of oncogenes that can be targeted therapeutically and the treatment of BRAF melanomas with RAF and MEK inhibitors results in rapid tumor regression. However, drug-induced rewiring generates...
8.
Warchol S, Krueger R, Nirmal A, Gaglia G, Jessup J, Ritch C, et al.
IEEE Trans Vis Comput Graph
. 2022 Sep;
29(1):106-116.
PMID: 36170403
New highly-multiplexed imaging technologies have enabled the study of tissues in unprecedented detail. These methods are increasingly being applied to understand how cancer cells and immune response change during tumor...
9.
Schapiro D, Yapp C, Sokolov A, Reynolds S, Chen Y, Sudar D, et al.
Nat Methods
. 2022 Mar;
19(3):262-267.
PMID: 35277708
No abstract available.
10.
Jessup J, Krueger R, Warchol S, Hoffer J, Muhlich J, Ritch C, et al.
IEEE Trans Vis Comput Graph
. 2021 Oct;
28(1):259-269.
PMID: 34606456
Inspection of tissues using a light microscope is the primary method of diagnosing many diseases, notably cancer. Highly multiplexed tissue imaging builds on this foundation, enabling the collection of up...