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Jeremy A Daniel

Explore the profile of Jeremy A Daniel including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 2697
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Recent Articles
1.
Oksenych V, Su D, Daniel J
Biomolecules . 2022 Jan; 12(1). PMID: 35053209
B lymphocyte development has two DNA recombination processes: V(D)J recombination of the immunoglobulin () gene variable region, and class switching of the constant regions from IgM to IgG, IgA, or...
2.
Ruth K, Day F, Hussain J, Martinez-Marchal A, Aiken C, Azad A, et al.
Nature . 2021 Aug; 596(7872):393-397. PMID: 34349265
Reproductive longevity is essential for fertility and influences healthy ageing in women, but insights into its underlying biological mechanisms and treatments to preserve it are limited. Here we identify 290...
3.
Hendriks I, Lyon D, Su D, Skotte N, Daniel J, Jensen L, et al.
Nat Commun . 2018 Jun; 9(1):2456. PMID: 29942033
Small ubiquitin-like modifiers (SUMOs) are post-translational modifications that play crucial roles in most cellular processes. While methods exist to study exogenous SUMOylation, large-scale characterization of endogenous SUMO2/3 has remained technically...
4.
Su D, Vanhee S, Soria R, Gyllenback E, Starnes L, Hojfeldt M, et al.
Proc Natl Acad Sci U S A . 2017 Oct; 114(44):E9328-E9337. PMID: 29078319
B cell receptor signaling and downstream NF-κB activity are crucial for the maturation and functionality of all major B cell subsets, yet the molecular players in these signaling events are...
5.
Xing M, Bjoras M, Daniel J, Alt F, Oksenych V
DNA Repair (Amst) . 2017 Aug; 57:133-138. PMID: 28759779
DNA double-strand breaks (DSBs) are recognized and repaired by the Classical Non-Homologous End-Joining (C-NHEJ) and Homologous Recombination pathways. C-NHEJ includes the core Ku70 and Ku80 (or Ku86) heterodimer that binds...
6.
Smith E, Gole B, Willis N, Soria R, Starnes L, Krumpelbeck E, et al.
Sci Rep . 2017 Mar; 7:44662. PMID: 28317934
DEK is a highly conserved chromatin-bound protein whose upregulation across cancer types correlates with genotoxic therapy resistance. Loss of DEK induces genome instability and sensitizes cells to DNA double strand...
7.
Hansen R, Mund A, Poulsen S, Sandoval M, Klement K, Tsouroula K, et al.
Nat Cell Biol . 2016 Nov; 18(12):1357-1366. PMID: 27820601
DNA double-strand breaks (DSBs) are highly cytotoxic DNA lesions, whose accurate repair by non-homologous end-joining (NHEJ) or homologous recombination (HR) is crucial for genome integrity and is strongly influenced by...
8.
Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte A, Lee J, et al.
Nature . 2016 Sep; 539(7629):456. PMID: 27680696
No abstract available.
9.
Larsen S, Sylvestersen K, Mund A, Lyon D, Mullari M, Madsen M, et al.
Sci Signal . 2016 Sep; 9(443):rs9. PMID: 27577262
The posttranslational modification of proteins by arginine methylation is functionally important, yet the breadth of this modification is not well characterized. Using high-resolution mass spectrometry, we identified 8030 arginine methylation...
10.
Kristiansen T, Gyllenback E, Zriwil A, Bjorklund T, Daniel J, Sitnicka E, et al.
Immunity . 2016 Aug; 45(2):346-57. PMID: 27533015
Hematopoietic stem cells (HSCs) undergo a functional switch in neonatal mice hallmarked by a decrease in self-renewing divisions and entry into quiescence. Here, we investigated whether the developmental attenuation of...