Jeoung-Eun Park
Overview
Explore the profile of Jeoung-Eun Park including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
197
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0
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Recent Articles
1.
Park J, Brand D, Rosloniec E, Yi A, Stuart J, Kang A, et al.
J Biol Chem
. 2020 Jan;
295(8):2239-2247.
PMID: 31932281
Multiple observations implicate T-cell dysregulation as a central event in the pathogenesis of rheumatoid arthritis. Here, we investigated mechanisms for suppressing T-cell activation via the inhibitory receptor leukocyte-associated immunoglobulin-like receptor...
2.
Park J, Majumdar S, Brand D, Rosloniec E, Yi A, Stuart J, et al.
Clin Immunol
. 2018 Apr;
192:50-57.
PMID: 29673901
The aim of this study was to understand how Syk affects peripheral T cell function. T cells from Syk chimeric mice and DR1 Syk CD4 conditional mice gave strong CD3-induced...
3.
Kim S, Easterling E, Price L, Smith S, Coligan J, Park J, et al.
J Immunol
. 2017 Sep;
199(8):2692-2700.
PMID: 28887430
Several observations implicate a critical role for T cell dysregulation as a central problem in rheumatoid arthritis. We investigated a mechanism for suppressing T cell activation by stimulating a natural...
4.
Upadhyay K, Park J, Yoon T, Halder P, Kim Y, Metcalfe V, et al.
J Immunol
. 2017 May;
198(11):4448-4457.
PMID: 28461572
Group B streptococci (GBS) are one of the leading causes of life-threatening illness in neonates. Proinflammatory responses to GBS mediated through host innate immune receptors play a critical role in...
5.
Park J, Rotondo J, Cullins D, Brand D, Yi A, Stuart J, et al.
J Immunol
. 2016 Nov;
197(12):4569-4575.
PMID: 27837109
Rheumatoid arthritis is an autoimmune disorder characterized by T cell dysregulation. We have shown that an altered peptide ligand (A9) activates T cells to use an alternate signaling pathway that...
6.
Myers L, Cullins D, Park J, Yi A, Brand D, Rosloniec E, et al.
Clin Immunol
. 2015 May;
160(2):188-97.
PMID: 25982319
Factors that drive T cells to signal through differing pathways remain unclear. We have shown that an altered peptide ligand (A9) activates T cells to utilize an alternate signaling pathway...
7.
Kim Y, Park J, Kwon K, Hong C, Yi A
PLoS One
. 2012 Aug;
7(8):e43970.
PMID: 22928050
As a part of the negative feedback mechanism, CpG DNA induces IRAK-M expression in monocytic cells. In the present study we investigated a biochemical signaling pathway and the transcription factors...
8.
Park J, Cullins D, Zalduondo L, Barnett S, Yi A, Kleinau S, et al.
J Biol Chem
. 2012 Apr;
287(23):19765-74.
PMID: 22511761
Mounting evidence from animal models has demonstrated that alterations in peptide-MHC interactions with the T cell receptor (TCR) can lead to dramatically different T cell outcomes. We have developed an...
9.
Kim Y, Park J, Brand D, Fitzpatrick E, Yi A
J Immunol
. 2010 Feb;
184(6):3145-56.
PMID: 20142359
Hypersensitivity pneumonitis is an interstitial lung disease that results from repeated pulmonary exposure to various organic Ags, including Saccharopolyspora rectivirgula, the causative agent of farmer's lung disease. Although the contributions...
10.
Tang B, Zhou J, Park J, Cullins D, Yi A, Kang A, et al.
Clin Immunol
. 2009 Jul;
133(1):145-53.
PMID: 19596610
We have previously described an analog peptide of type II collagen (CII) that can suppress collagen-induced arthritis (CIA). This analog peptide represents CII(245-270), the immunodominant epitope of CII, but with...