David D Brand
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Explore the profile of David D Brand including associated specialties, affiliations and a list of published articles.
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63
Citations
1941
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Recent Articles
1.
Walton B, Shattuck-Brandt R, Hamann C, Tung V, Colazo J, Brand D, et al.
Osteoarthritis Cartilage
. 2024 Dec;
33(2):231-240.
PMID: 39706287
Objective: Investigational cell therapies have been developed as disease-modifying agents for the treatment of osteoarthritis (OA), including those that inducibly respond to inflammatory factors driving OA progression. However, dysregulated inflammatory...
2.
Dong W, Tian C, Li Z, Bounds M, Ma J, Brand D, et al.
Sci Rep
. 2024 Aug;
14(1):19889.
PMID: 39191800
When IL-1 receptor antagonist (IL-1rn) is knocked out, mice have shown strain background dependent and major QTL regulated susceptibility to spontaneously inflammatory arthritis disease (SAD). The impact on bone properties...
3.
Singh S, Prislovsky A, Ngwa D, Munkhsaikhan U, Abidi A, Brand D, et al.
Front Immunol
. 2024 Apr;
15:1385085.
PMID: 38650931
The biosynthesis of C-reactive protein (CRP) in the liver is increased in inflammatory diseases including rheumatoid arthritis. Previously published data suggest a protective function of CRP in arthritis; however, the...
4.
Walton B, Shattuck-Brandt R, Hamann C, Tung V, Colazo J, Brand D, et al.
bioRxiv
. 2024 Feb;
PMID: 38352576
Objective: Investigational cell therapies have been developed as disease-modifying agents for the treatment of osteoarthritis (OA), including those that inducibly respond to inflammatory factors driving OA progression. However, dysregulated inflammatory...
5.
Zhao J, Liu Y, Shi X, Dang J, Liu Y, Li S, et al.
J Adv Res
. 2023 May;
58:79-91.
PMID: 37169220
Introduction: Rheumatoid arthritis (RA) is a systemic autoimmune disease with limited treatment success, characterized by chronic inflammation and progressive cartilage and bone destruction. Accumulating evidence has shown that neutrophil extracellular...
6.
Bhatti F, Jeong Y, Kim D, Yi A, Brand D, Hasty K, et al.
Antioxidants (Basel)
. 2022 Sep;
11(9).
PMID: 36139857
The pathophysiology of post-traumatic arthritis (PTOA) is not fully understood. This study used non-invasive repetitive mechanical loading (ML) mouse models to study biochemical, biomechanical, and pain-related behavioral changes induced in...
7.
Myers L, Ouyang Y, Patel J, Odens H, Woo-Rasberry V, Park J, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077232
Citrullination of proteins plays an important role in protein function and it has recently become clear that citrullinated proteins play a role in immune responses. In this study we examined...
8.
Karydis A, Sandal I, Luo J, Prislovsky A, Gamboa A, Rosloniec E, et al.
PLoS One
. 2022 Feb;
17(2):e0263754.
PMID: 35108337
[This corrects the article DOI: 10.1371/journal.pone.0250177.].
9.
Myers L, Winstead M, Kee J, Park J, Zhang S, Li W, et al.
Int J Mol Sci
. 2021 Dec;
22(24).
PMID: 34948139
Vitamin D plays a crucial role in regulation of the immune response. However, treatment of autoimmune diseases with 1,25-dihydroxyvitamin D3 [1,25(OH)D3] doses sufficient to be effective is prohibitive due to...
10.
Rosloniec E, Whittington K, Proslovsky A, Brand D
Curr Protoc
. 2021 Dec;
1(12):e313.
PMID: 34890495
The collagen-induced arthritis mouse model is a widely studied autoimmune model of rheumatoid arthritis. In this model, autoimmune arthritis is induced by immunization of genetically susceptible strains of mice with...