Jens van den Brandt
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Explore the profile of Jens van den Brandt including associated specialties, affiliations and a list of published articles.
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53
Citations
1287
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Recent Articles
1.
Smolinska A, Singer K, Golchert J, Smyczynska U, Fendler W, Sendler M, et al.
Cancers (Basel)
. 2022 Sep;
14(17).
PMID: 36077614
Pancreatic ductal adenocarcinoma (PDAC), due to its genomic heterogeneity and lack of effective treatment, despite decades of intensive research, will become the second leading cause of cancer-related deaths by 2030....
2.
Przybylski G, Korsak D, Izykowska K, Nowicka K, Zalewski T, Tubacka M, et al.
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563322
The B-cell CLL/lymphoma 11B gene (BCL11B) plays a crucial role in T-cell development, but its role in T-cell malignancies is still unclear. To study its role in the development of...
3.
Artelt N, Ritter A, Leitermann L, Kliewe F, Schluter R, Simm S, et al.
PLoS One
. 2021 Dec;
16(12):e0260878.
PMID: 34879092
Proper and size selective blood filtration in the kidney depends on an intact morphology of podocyte foot processes. Effacement of interdigitating podocyte foot processes in the glomeruli causes a leaky...
4.
Raafat D, Mrochen D, AlSholui F, Heuser E, Ryll R, Pritchett-Corning K, et al.
Toxins (Basel)
. 2020 Jan;
12(2).
PMID: 31991690
Rats are a reservoir of human- and livestock-associated methicillin-resistant (MRSA). However, the composition of the natural population in wild and laboratory rats is largely unknown. Here, 144 nasal isolates from...
5.
Bracke A, Domanska G, Bracke K, Harzsch S, van den Brandt J, Broker B, et al.
J Exp Neurosci
. 2019 Nov;
13:1179069519883580.
PMID: 31765441
Currently, it is controversially discussed whether a relationship between obesity and cognition exists. We here analyzed a mouse model of obesity (leptin-deficient mice) to study the effects of obesity on...
6.
Artelt N, Ludwig T, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, et al.
J Am Soc Nephrol
. 2018 May;
29(6):1662-1678.
PMID: 29720549
Podocyte loss and effacement of interdigitating podocyte foot processes are the major cause of a leaky filtration barrier and ESRD. Because the complex three-dimensional morphology of podocytes depends on the...
7.
Mrochen D, Grumann D, Schulz D, Gumz J, Trube P, Pritchett-Corning K, et al.
Int J Med Microbiol
. 2017 Nov;
308(6):598-606.
PMID: 29174495
We previously reported that laboratory mice from all global vendors are frequently colonized with Staphylococcus aureus (S. aureus). Genotyping of a snap sample of murine S. aureus isolates from Charles...
8.
Schulz D, Grumann D, Trube P, Pritchett-Corning K, Johnson S, Reppschlager K, et al.
Front Cell Infect Microbiol
. 2017 May;
7:152.
PMID: 28512627
Whether mice are an appropriate model for infection and vaccination studies is a matter of debate, because they are not considered as natural hosts of . We previously identified a...
9.
Fischer H, Sie C, Schumann E, Witte A, Dressel R, van den Brandt J, et al.
J Immunol
. 2017 Jan;
198(5):1910-1920.
PMID: 28115529
T cell activation is an energy-demanding process fueled by increased glucose consumption and accompanied by upregulation of the insulin receptor (INSR). In this article, we report that silencing the INSR...
10.
Kindt F, Hammer E, Kemnitz S, Blumenthal A, Klemm P, Schluter R, et al.
Br J Pharmacol
. 2016 Nov;
174(2):163-176.
PMID: 27858997
Background And Purpose: Therapeutic options for treating glomerulopathies, the main cause of chronic kidney disease, are limited. Podocyte dedifferentiation is a major event in the pathogenesis of glomerulopathies. The goal...