Jens Peter von Kries
Overview
Explore the profile of Jens Peter von Kries including associated specialties, affiliations and a list of published articles.
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55
Citations
1386
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Recent Articles
1.
Hentsch A, Guberman M, Radetzki S, Kaushik S, Huizenga M, Paul J, et al.
Angew Chem Int Ed Engl
. 2025 Feb;
64(10):e202413405.
PMID: 39916545
Monoacylglycerol lipase (MAGL) is a key enzyme for signal termination in the endocannabinoid system (ECS). MAGL inhibition results in indirect activation of the cannabinoid receptors, which offers unique advantages for...
2.
van Hoof S, Kreye J, Cordero-Gomez C, Hoffmann J, Reincke S, Sanchez-Sendin E, et al.
Brain Behav Immun
. 2024 Aug;
122:266-278.
PMID: 39142424
Anti-contactin associated protein receptor 2 (CASPR2) encephalitis is a severe autoimmune encephalitis with a variable clinical phenotype including behavioral abnormalities, cognitive decline, epileptic seizures, peripheral nerve hyperexcitability and neuropathic pain....
3.
Mohd S, Oder A, Specker E, Neuenschwander M, von Kries J, Daumke O
PLoS One
. 2024 Jul;
19(7):e0302704.
PMID: 39074100
Eps15 (epidermal growth factor receptor pathway substrate 15) homology domain-containing proteins (EHDs) comprise a family of eukaryotic dynamin-related ATPases that participate in various endocytic membrane trafficking pathways. Dysregulation of EHDs...
4.
Mach L, Omran A, Bouma J, Radetzki S, Sykes D, Guba W, et al.
J Med Chem
. 2024 Jul;
67(14):11841-11867.
PMID: 38990855
The cannabinoid receptor type 1 (CBR) is pivotal within the endocannabinoid system regulating various signaling cascades with effects in appetite regulation, pain perception, memory formation, and thermoregulation. Still, understanding of...
5.
Mehboob R, Oehme P, Anwar T, von Kries J
Front Neurol
. 2024 Jun;
15:1370454.
PMID: 38872816
Severe acute respiratory syndrome corona virus 2 (SARS CoV-2) is the cause of Corona virus disease 2019 (COVID-19), which turned into a pandemic in late 2019 and early 2020. SARS...
6.
Brenner M, Zink C, Witzinger L, Keller A, Hadamek K, Bothe S, et al.
Elife
. 2024 Jun;
13.
PMID: 38856179
Vitamin B6 deficiency has been linked to cognitive impairment in human brain disorders for decades. Still, the molecular mechanisms linking vitamin B6 to these pathologies remain poorly understood, and whether...
7.
Becker P, Guth-Steffens M, Lazarow K, Sonntag N, Braun D, Masfaka I, et al.
Thyroid
. 2024 May;
34(7):920-930.
PMID: 38801167
3,5,3'-Triiodothyroacetic acid (TRIAC) is a T-receptor agonist pharmacologically used in patients to mitigate T resistance. It is additionally explored to treat some symptoms of patients with inactivating mutations in the...
8.
Gazzi T, Lesina M, Wang Q, Berninger A, Radetzki S, Demir I, et al.
Angew Chem Int Ed Engl
. 2024 Apr;
63(26):e202318485.
PMID: 38608197
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and lethal malignancy with extremely poor patient survival rates. A key reason for the poor prognosis is the lack of effective diagnostic...
9.
Specker E, Wesolowski R, Schutz A, Matthes S, Mallow K, Wasinska-Kalwa M, et al.
J Med Chem
. 2023 Oct;
66(21):14866-14896.
PMID: 37905925
Tryptophan hydroxylases catalyze the first and rate-limiting step in the biosynthesis of serotonin, a well-known neurotransmitter that plays an important role in multiple physiological functions. A reduction of serotonin levels,...
10.
Yan S, Schope P, Lewis J, Putzker K, Uhrig U, Specker E, et al.
Biomed Pharmacother
. 2023 Oct;
168:115698.
PMID: 37865992
Metastasis is directly linked to poor prognosis of cancer patients and warrants search for effective anti-metastatic drugs. MACC1 is a causal key molecule for metastasis. High MACC1 expression is prognostic...