Jens C Otte
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Explore the profile of Jens C Otte including associated specialties, affiliations and a list of published articles.
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16
Citations
161
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Recent Articles
1.
Otte J, Hollnagel H, Nagel C, Gerhardt R, Wohlleben W, Vallotton N, et al.
Regul Toxicol Pharmacol
. 2023 Sep;
144:105495.
PMID: 37730194
Polymers are a very large class of chemicals comprising often complex molecules with multiple functions used in everyday products. The EU Commission is seeking to develop environmental and human health...
2.
Holmes C, Maltby L, Sweeney P, Thorbek P, Otte J, Marshall S
Ecotoxicol Environ Saf
. 2022 Oct;
246:114143.
PMID: 36201920
Chemical exposure concentrations and the composition of ecological receptors (e.g., species) vary in space and time, resulting in landscape-scale (e.g. catchment) heterogeneity. Current regulatory, prospective chemical risk assessment frameworks do...
3.
Redman A, Bietz J, Davis J, Lyon D, Maloney E, Ott A, et al.
Integr Environ Assess Manag
. 2021 Nov;
18(4):868-887.
PMID: 34730270
Assessing the persistence of chemicals in the environment is a key element in existing regulatory frameworks to protect human health and ecosystems. Persistence in the environment depends on many fate...
4.
Takamiya M, Stegmaier J, Kobitski A, Schott B, Weger B, Margariti D, et al.
PLoS Genet
. 2020 Jun;
16(6):e1008774.
PMID: 32555736
Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced the origin of the ocular NC cells to two distinct NC populations that differ...
5.
Schott B, Traub M, Schlagenhauf C, Takamiya M, Antritter T, Bartschat A, et al.
PLoS Comput Biol
. 2018 Apr;
14(4):e1006128.
PMID: 29672531
State-of-the-art light-sheet and confocal microscopes allow recording of entire embryos in 3D and over time (3D+t) for many hours. Fluorescently labeled structures can be segmented and tracked automatically in these...
6.
Otte J, Schultz B, Fruth D, Fabian E, van Ravenzwaay B, Hidding B, et al.
Toxicol Sci
. 2017 Sep;
159(1):86-93.
PMID: 28903500
Early life stages of zebrafish (Danio rerio, zf) are gaining attention as an alternative invivo test system for drug discovery, early developmental toxicity screenings and chemical testing in ecotoxicological and...
7.
Hausen J, Otte J, Legradi J, Yang L, Strahle U, Fenske M, et al.
Environ Sci Pollut Res Int
. 2017 Apr;
25(5):4023-4036.
PMID: 28391457
In ecotoxicology, transcriptomics is an effective way to detect gene expression changes in response to environmental pollutants. Such changes can be used to identify contaminants or contaminant classes and can...
8.
Hausen J, Otte J, Strahle U, Hammers-Wirtz M, Hollert H, Keiter S, et al.
Environ Sci Pollut Res Int
. 2015 Jul;
22(21):16384-92.
PMID: 26178833
Transcriptomics is often used to investigate changes in an organism's genetic response to environmental contamination. Data noise can mask the effects of contaminants making it difficult to detect responding genes....
9.
Kobitski A, Otte J, Takamiya M, Schafer B, Mertes J, Stegmaier J, et al.
Sci Rep
. 2015 Feb;
5:8601.
PMID: 25712513
A new era in developmental biology has been ushered in by recent advances in the quantitative imaging of all-cell morphogenesis in living organisms. Here we have developed a light-sheet fluorescence...
10.
Bluhm K, Otte J, Yang L, Zinsmeister C, Legradi J, Keiter S, et al.
PLoS One
. 2014 Sep;
9(9):e106523.
PMID: 25187966
Purpose: Recently, a proof-of-concept study revealed the suitability of transcriptome analyses to obtain and assess changes in the abundance of transcripts in zebrafish (Danio rerio) embryos after exposure to organic...