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Jennifer Van Eyk

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Articles 59
Citations 2543
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Recent Articles
1.
Stocksdale J, Leventhal M, Lam S, Xu Y, Wang Y, Wang K, et al.
bioRxiv . 2025 Mar; PMID: 40060574
Huntington's Disease (HD) is caused by a CAG repeat expansion in the gene encoding Huntingtin (HTT . While normal HTT function appears impacted by the mutation, the specific pathways unique...
2.
Silva T, Hutchins E, Zhao W, Ciani Y, Kim M, Mariscal J, et al.
bioRxiv . 2024 Sep; PMID: 39229160
Extracellular vesicles (EVs) are heterogenous in size, biogenesis, cargo and function. Beside small EVs, aggressive tumor cells release a population of particularly large EVs, namely large oncosomes (LO). This study...
3.
Ibrahim A, Ciullo A, Yamaguchi S, Li C, Antes T, Jones X, et al.
Proteomics Clin Appl . 2024 Mar; 18(5):e2300128. PMID: 38444254
Purpose: Micropeptides are an emerging class of proteins that play critical roles in cell signaling. Here, we describe the discovery of a novel micropeptide, dubbed slitharin (Slt), in conditioned media...
4.
Clouthier K, Taylor A, Xuhuai J, Liu Y, Parker S, Van Eyk J, et al.
World J Pediatr Congenit Heart Surg . 2023 Dec; 15(2):162-173. PMID: 38128927
Despite surgical advances, children with tetralogy of Fallot/pulmonary atresia/major aortopulmonary collaterals (TOF/PA/MAPCAs) are subject to chronic right ventricular (RV) pressure and volume overload. Current diagnostic tools do not identify adverse...
5.
Muranaka H, Hendifar A, Osipov A, Moshayedi N, Placencio-Hickok V, Tatonetti N, et al.
Cancers (Basel) . 2023 Jun; 15(11). PMID: 37296982
Pancreatic cancer (PC) is one of the deadliest cancers. Developing biomarkers for chemotherapeutic response prediction is crucial for improving the dismal prognosis of advanced-PC patients (pts). To evaluate the potential...
6.
Kreimer S, Binek A, Chazarin B, Cho J, Haghani A, Hutton A, et al.
Anal Chem . 2023 Jun; 95(24):9145-9150. PMID: 37289937
Identification and proteomic characterization of rare cell types within complex organ-derived cell mixtures is best accomplished by label-free quantitative mass spectrometry. High throughput is required to rapidly survey hundreds to...
7.
Gatto L, Aebersold R, Cox J, Demichev V, Derks J, Emmott E, et al.
Nat Methods . 2023 Mar; 20(3):375-386. PMID: 36864200
Analyzing proteins from single cells by tandem mass spectrometry (MS) has recently become technically feasible. While such analysis has the potential to accurately quantify thousands of proteins across thousands of...
8.
Kreimer S, Binek A, Chazarin B, Cho J, Haghani A, Hutton A, et al.
bioRxiv . 2023 Jan; PMID: 36711540
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9.
Park E, Ito K, Iqbal R, Amigues I, Bokhari S, Van Eyk J, et al.
Arthritis Res Ther . 2022 Aug; 24(1):184. PMID: 35932048
Background: Diastolic dysfunction (DD) is more prevalent in patients with rheumatoid arthritis (RA) compared to the general population. However, its evolution over time and its significant clinical predictors remain uncharacterized....
10.
Stachowicz A, Sundararaman N, Venkatraman V, Van Eyk J, Fert-Bober J
Methods Mol Biol . 2021 Dec; 2420:107-126. PMID: 34905169
Citrullination, the Ca-driven enzymatic conversion of arginine residues to citrulline, is a posttranslational modification, implicated in several physiological and pathological processes. Several methods to detect citrullinated proteins have been developed,...