Jennifer Sambrook
Overview
Explore the profile of Jennifer Sambrook including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
2874
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0
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Recent Articles
1.
Akbari P, Vuckovic D, Stefanucci L, Jiang T, Kundu K, Kreuzhuber R, et al.
Nat Commun
. 2023 Aug;
14(1):5023.
PMID: 37596262
Blood cells contain functionally important intracellular structures, such as granules, critical to immunity and thrombosis. Quantitative variation in these structures has not been subjected previously to large-scale genetic analysis. We...
2.
McMahon A, Kaptoge S, Walker M, Mehenny S, Gilchrist P, Sambrook J, et al.
Trials
. 2023 Aug;
24(1):512.
PMID: 37563721
Background: Vasovagal reactions (VVRs) are the most common acute complications of blood donation. Responsible for substantial morbidity, they also reduce the likelihood of repeated donations and are disruptive and costly...
3.
Serra E, Schwerd T, Moutsianas L, Cavounidis A, Fachal L, Pandey S, et al.
Nat Commun
. 2022 Jun;
13(1):3576.
PMID: 35732629
No abstract available.
4.
Bell S, Sweeting M, Ramond A, Chung R, Kaptoge S, Walker M, et al.
Transfus Med
. 2020 Dec;
31(2):94-103.
PMID: 33341984
Objective: To compare four haemoglobin measurement methods in whole blood donors. Background: To safeguard donors, blood services measure haemoglobin concentration in advance of each donation. NHS Blood and Transplant's (NHSBT)...
5.
Gleadall N, Veldhuisen B, Gollub J, Butterworth A, Ord J, Penkett C, et al.
Blood Adv
. 2020 Aug;
4(15):3495-3506.
PMID: 32750130
Each year, blood transfusions save millions of lives. However, under current blood-matching practices, sensitization to non-self-antigens is an unavoidable adverse side effect of transfusion. We describe a universal donor typing...
6.
Serra E, Schwerd T, Moutsianas L, Cavounidis A, Fachal L, Pandey S, et al.
Nat Commun
. 2020 Feb;
11(1):995.
PMID: 32081864
Very-early-onset inflammatory bowel disease (VEO-IBD) is a heterogeneous phenotype associated with a spectrum of rare Mendelian disorders. Here, we perform whole-exome-sequencing and genome-wide genotyping in 145 patients (median age-at-diagnosis of...
7.
Davies M, Kalsi G, Armour C, Jones I, McIntosh A, Smith D, et al.
Behav Res Ther
. 2019 Nov;
123:103503.
PMID: 31715324
Background: Anxiety and depression are common, debilitating and costly. These disorders are influenced by multiple risk factors, from genes to psychological vulnerabilities and environmental stressors, but research is hampered by...
8.
Ji S, Juran B, Mucha S, Folseraas T, Jostins L, Melum E, et al.
Nat Genet
. 2016 Dec;
49(2):269-273.
PMID: 27992413
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct destruction; ∼75% of patients have comorbid inflammatory bowel disease (IBD). We undertook the largest genome-wide association study...
9.
Astle W, Elding H, Jiang T, Allen D, Ruklisa D, Mann A, et al.
Cell
. 2016 Nov;
167(5):1415-1429.e19.
PMID: 27863252
Many common variants have been associated with hematological traits, but identification of causal genes and pathways has proven challenging. We performed a genome-wide association analysis in the UK Biobank and...
10.
Moore C, Bolton T, Walker M, Kaptoge S, Allen D, Daynes M, et al.
Trials
. 2016 Sep;
17(1):458.
PMID: 27645285
Background: The interpretation of trial results can be helped by understanding how generalisable they are to the target population for which inferences are intended. INTERVAL, a large pragmatic randomised trial...