Jennifer Permuth-Wey
Overview
Explore the profile of Jennifer Permuth-Wey including associated specialties, affiliations and a list of published articles.
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30
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1027
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Recent Articles
11.
Chen D, Davis-Yadley A, Huang P, Husain K, Centeno B, Permuth-Wey J, et al.
PLoS One
. 2015 Aug;
10(8):e0133562.
PMID: 26247463
The outcomes of patients treated with surgery for early stage pancreatic ductal adenocarcinoma (PDAC) are variable with median survival ranging from 6 months to more than 5 years. This challenge...
12.
Kar S, Tyrer J, Li Q, Lawrenson K, Aben K, Anton-Culver H, et al.
Cancer Epidemiol Biomarkers Prev
. 2015 Jul;
24(10):1574-84.
PMID: 26209509
Background: Genome-wide association studies (GWAS) have so far reported 12 loci associated with serous epithelial ovarian cancer (EOC) risk. We hypothesized that some of these loci function through nearby transcription...
13.
Chornokur G, Lin H, Tyrer J, Lawrenson K, Dennis J, Amankwah E, et al.
PLoS One
. 2015 Jun;
10(6):e0128106.
PMID: 26091520
Background: Defective cellular transport processes can lead to aberrant accumulation of trace elements, iron, small molecules and hormones in the cell, which in turn may promote the formation of reactive...
14.
Stegeman S, Amankwah E, Klein K, OMara T, Kim D, Lin H, et al.
Cancer Discov
. 2015 Feb;
5(4):368-79.
PMID: 25691096
Unlabelled: Prostate cancer is the second most common malignancy among men worldwide. Genome-wide association studies have identified 100 risk variants for prostate cancer, which can explain approximately 33% of the...
15.
Permuth-Wey J, Chen Y, Fisher K, McCarthy S, Qu X, Lloyd M, et al.
PLoS One
. 2015 Jan;
10(1):e0116869.
PMID: 25607660
Background: Intraductal papillary mucinous neoplasms (IPMNs) are pancreatic ductal adenocarcinoma (PDAC) precursors. Differentiating between high-risk IPMNs that warrant surgical resection and low-risk IPMNs that can be monitored is a significant...
16.
Richards E, Zhang G, Li Z, Permuth-Wey J, Challa S, Li Y, et al.
J Biol Chem
. 2015 Jan;
290(11):6857-67.
PMID: 25605728
Long noncoding RNAs (lncRNAs) are emerging as key regulators in various biological processes. Epithelial-to-mesenchymal transition (EMT) is a developmental process hijacked by tumor cells to depart from the primary tumor...
17.
Prescott J, Bertrand K, Reid B, Permuth-Wey J, De Vivo I, Cramer D, et al.
Front Oncol
. 2014 Nov;
4:286.
PMID: 25368842
Introduction: Experimental studies suggest vitamin D inhibits ovarian carcinogenesis. Yet, epidemiologic studies of ovarian cancer risk and lifestyle correlates of vitamin D status, plasma 25-hydroxyvitamin D [25(OH)D], or vitamin D...
18.
Chen N, Chon H, Xiong Y, Marchion D, Judson P, Hakam A, et al.
Oncol Rep
. 2013 Nov;
31(1):376-83.
PMID: 24220856
Paclitaxel is a mainstay of treatment for many solid tumors, and frequently, clinical outcome is influenced by paclitaxel sensitivity. Despite this, our understanding of the molecular basis of paclitaxel response...
19.
Permuth-Wey J, Lawrenson K, Shen H, Velkova A, Tyrer J, Chen Z, et al.
Nat Commun
. 2013 Mar;
4:1627.
PMID: 23535648
Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3'...
20.
Xu C, Xu M, Tan L, Yang H, Permuth-Wey J, Kruk P, et al.
J Biol Chem
. 2012 Aug;
287(42):34970-34978.
PMID: 22927443
Previous studies have shown aberrant expression of miR-214 in human malignancy. Elevated miR-214 is associated with chemoresistance and metastasis. In this study, we identified miR-214 regulation of ovarian cancer stem...