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Jennifer M Rosenbluth

Explore the profile of Jennifer M Rosenbluth including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 1034
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Recent Articles
1.
Nguyen H, An K, Ito Y, Kharbikar B, Sheng R, Paredes B, et al.
Nat Biotechnol . 2025 Feb; PMID: 39905264
Tumors exhibit an increased ability to obtain and metabolize nutrients. Here, we implant engineered adipocytes that outcompete tumors for nutrients and show that they can substantially reduce cancer progression, a...
2.
Cho N, Guldberg S, Nabet B, Yu J, Kim E, Hiam-Galvez K, et al.
Cancer Immunol Res . 2024 Oct; 13(2):229-244. PMID: 39404741
Resistance to immune checkpoint inhibitors (ICI) is common, even in tumors with T-cell infiltration. We thus investigated consequences of ICI-induced T-cell infiltration in the microenvironment of resistant tumors. T cells...
3.
Greenwood H, Maldonado Rodas C, Freimanis R, Glencer A, Miller P, Mukhtar R, et al.
NPJ Breast Cancer . 2024 Aug; 10(1):71. PMID: 39098868
New approaches are needed to determine which ductal carcinoma in situ (DCIS) is at high risk for progression to invasive ductal carcinoma (IDC). We retrospectively studied DCIS patients who declined...
4.
Graham A, Khoo M, Srivastava V, Viragova S, Kim H, Parekh K, et al.
bioRxiv . 2024 Feb; PMID: 38370663
Organoids are powerful models of tissue physiology, yet their applications remain limited due to their relatively simple morphology and high organoid-to-organoid structural variability. To address these limitations we developed a...
5.
Garrido-Castro A, Regan M, Niman S, Nakhlis F, Remolano C, Rosenbluth J, et al.
NPJ Breast Cancer . 2023 Jun; 9(1):50. PMID: 37268625
Inflammatory breast cancer (IBC) is a rare, aggressive form of breast cancer that presents as de novo metastatic disease in 20-30% of cases, with one-third of cases demonstrating HER2-positivity. There...
6.
Nguyen H, Sheng R, Murray E, Ito Y, Bruck M, Biellak C, et al.
bioRxiv . 2023 Apr; PMID: 37034710
Tumors acquire an increased ability to obtain and metabolize nutrients. Here, we engineered and implanted adipocytes to outcompete tumors for nutrients and show that they can substantially reduce cancer progression....
7.
Glencer A, Miller P, Greenwood H, Maldonado Rodas C, Freimanis R, Basu A, et al.
Cancer Res Commun . 2023 Mar; 2(12):1579-1589. PMID: 36970720
Significance: A retrospective analysis of 71 patients with DCIS who did not undergo upfront surgery demonstrated that breast MRI features after short-term exposure to endocrine therapy identify those at high...
8.
Gray G, Li C, Rosenbluth J, Selfors L, Girnius N, Lin J, et al.
Dev Cell . 2022 May; 57(11):1400-1420.e7. PMID: 35617956
The breast is a dynamic organ whose response to physiological and pathophysiological conditions alters its disease susceptibility, yet the specific effects of these clinical variables on cell state remain poorly...
9.
Hirko K, Regan M, Remolano M, Schlossman J, Harrison B, Yeh E, et al.
Am J Clin Oncol . 2021 Jun; 44(9):449-455. PMID: 34149037
Objectives: Dermal lymphatic invasion (DLI) with tumor emboli is a common pathologic characteristic of inflammatory breast cancer (IBC), although its presence is not required for diagnosis. We examined whether documented...
10.
Dekkers J, van Vliet E, Sachs N, Rosenbluth J, Kopper O, Rebel H, et al.
Nat Protoc . 2021 Mar; 16(4):1936-1965. PMID: 33692550
Organoid technology has revolutionized the study of human organ development, disease and therapy response tailored to the individual. Although detailed protocols are available for the generation and long-term propagation of...