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Jennifer K Spinler

Explore the profile of Jennifer K Spinler including associated specialties, affiliations and a list of published articles. Areas
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Articles 46
Citations 1201
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Recent Articles
1.
Midani F, Danhof H, Mathew N, Ardis C, Garey K, Spinler J, et al.
mSystems . 2025 Feb; :e0107524. PMID: 40013784
is a gram-positive spore-forming pathogen that commonly causes diarrheal infections in the developed world. Although is a genetically diverse species, certain ribotypes are overrepresented in human infections, and it is...
2.
Hankins J, Johnson C, Sanchez B, Serrano A, Runge J, Spinler J, et al.
Pediatr Infect Dis J . 2025 Jan; 44(2):118-124. PMID: 39886927
Background: Group A Streptococcus (GAS) infections can cause a range of disease manifestations and severity, including invasive infections that can lead to death. In 2022-2023, there was an increased number...
3.
Midani F, Danhof H, Mathew N, Ardis C, Garey K, Spinler J, et al.
bioRxiv . 2024 Aug; PMID: 39185189
Importance: The gut pathogen utilizes a wide range of carbon sources. Microbial communities can be rationally designed to combat by depleting its preferred nutrients in the gut. However, is genetically...
4.
Li G, Gopchandani K, Brazer N, Tippett A, Choi C, Hsiao H, et al.
Open Forum Infect Dis . 2024 Aug; 11(8):ofae443. PMID: 39183814
Background: Coronavirus disease 2019 (COVID-19) continues to cause hospitalizations and severe disease in children and adults. Methods: This study compared the risk factors, symptoms, and outcomes of children and adults...
5.
Engevik K, Hazzard A, Puckett B, Hoch K, Haidacher S, Haag A, et al.
Syst Appl Microbiol . 2024 Jul; 47(5):126539. PMID: 39029335
Histamine is an important biogenic amine known to impact a variety of patho-physiological processes ranging from allergic reactions, gut-mediated anti-inflammatory responses, and neurotransmitter activity. Histamine is found both endogenously within...
6.
Horvath T, Haidacher S, Engevik M, Luck B, Ruan W, Ihekweazu F, et al.
Nat Protoc . 2022 Nov; 18(2):490-529. PMID: 36352124
Interest in the communication between the gastrointestinal tract and central nervous system, known as the gut-brain axis, has prompted the development of quantitative analytical platforms to analyze microbe- and host-derived...
7.
Horvath T, Ihekweazu F, Haidacher S, Ruan W, Engevik K, Fultz R, et al.
iScience . 2022 May; 25(5):104158. PMID: 35494230
Gut microbes can synthesize multiple neuro-active metabolites. We profiled neuro-active compounds produced by the gut commensal and by LC-MS/MS. We found that generates acetic acid, propionic acid, isobutyric acid, and...
8.
Norsigian C, Danhof H, Brand C, Midani F, Broddrick J, Savidge T, et al.
Proc Natl Acad Sci U S A . 2022 Apr; 119(18):e2119396119. PMID: 35476524
Combatting Clostridioides difficile infections, a dominant cause of hospital-associated infections with incidence and resulting deaths increasing worldwide, is complicated by the frequent emergence of new virulent strains. Here, we employ...
9.
Fultz R, Ticer T, Ihekweazu F, Horvath T, Haidacher S, Hoch K, et al.
Front Microbiol . 2021 Dec; 12:745469. PMID: 34899632
Bacteroidetes are the most common bacterial phylum in the mammalian intestine and the effects of several spp. on multiple facets of host physiology have been previously described. Of the spp.,...
10.
Spinler J, Raza S, Thapa S, Venkatachalam A, Scott T, Runge J, et al.
J Mol Diagn . 2021 Nov; 24(2):158-166. PMID: 34775029
Hospital-acquired infections pose significant costly global challenges to patient care. Rapid and sensitive methods to identify potential outbreaks are integral to infection control measures. Whole-genome sequencing (WGS)-based bacterial strain typing...