James Versalovic
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Explore the profile of James Versalovic including associated specialties, affiliations and a list of published articles.
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166
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10010
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Recent Articles
1.
Engevik K, Hazzard A, Puckett B, Hoch K, Haidacher S, Haag A, et al.
Syst Appl Microbiol
. 2024 Jul;
47(5):126539.
PMID: 39029335
Histamine is an important biogenic amine known to impact a variety of patho-physiological processes ranging from allergic reactions, gut-mediated anti-inflammatory responses, and neurotransmitter activity. Histamine is found both endogenously within...
2.
Horvath T, Haidacher S, Engevik M, Luck B, Ruan W, Ihekweazu F, et al.
Nat Protoc
. 2022 Nov;
18(2):490-529.
PMID: 36352124
Interest in the communication between the gastrointestinal tract and central nervous system, known as the gut-brain axis, has prompted the development of quantitative analytical platforms to analyze microbe- and host-derived...
3.
Tierney B, Versalovic J, Fasano A, Petrosino J, Chumpitazi B, Mayer E, et al.
Pediatr Res
. 2022 Nov;
93(7):2005-2013.
PMID: 36319696
Background: Oral microbial therapy has been studied as an intervention for a range of gastrointestinal disorders. Though research suggests that microbial exposure may affect the gastrointestinal system, motility, and host...
4.
Oezguen N, Yilmaz V, Horvath T, Akbayir E, Haidacher S, Hoch K, et al.
Mult Scler Relat Disord
. 2022 Oct;
68:104239.
PMID: 36279598
Background: 3-phenyllactic acid (PLA) is produced by both intestinal bacteria and the human host. PLA exists in its D- and L- chiral forms. It modulates human immune functions, thereby acting...
5.
Horvath T, Ihekweazu F, Haidacher S, Ruan W, Engevik K, Fultz R, et al.
iScience
. 2022 May;
25(5):104158.
PMID: 35494230
Gut microbes can synthesize multiple neuro-active metabolites. We profiled neuro-active compounds produced by the gut commensal and by LC-MS/MS. We found that generates acetic acid, propionic acid, isobutyric acid, and...
6.
Boonma P, Shapiro J, Hollister E, Badu S, Wu Q, Weidler E, et al.
Front Pain Res (Lausanne)
. 2022 Mar;
2:691689.
PMID: 35295488
Little is known regarding the clinical impact of treatment and treatment duration of probiotic VSL#3 on gut and microbiome function in irritable bowel syndrome (IBS). As part of a safety...
7.
Krishna M, Engevik M, Queliza K, Britto S, Shah R, Ruan W, et al.
FASEB Bioadv
. 2022 Feb;
4(2):109-120.
PMID: 35141475
The purpose of our experiment was to explore how stochastic (inter-individual variation) gut microbiome composition may link to inflammatory bowel disease (IBD) susceptibility and guide the development of a perinatal...
8.
Thapa S, Luna R, Chumpitazi B, Oezguen N, Abdel-Rahman S, Garg U, et al.
Clin Transl Sci
. 2022 Jan;
15(4):1036-1049.
PMID: 35048535
Peppermint oil (PMO) is effective in the treatment of functional abdominal pain disorders, but its mechanism of action is unclear. Evidence suggests PMO has microbicidal activity. We investigated the effect...
9.
Devaraj S, Poventud-Fuentes I, Girotto M, Monroe J, Boom J, Delclos G, et al.
Pract Lab Med
. 2022 Jan;
28:e00261.
PMID: 34977312
To gain insights on the heterogeneity of immune responses to vaccination against SARS-CoV-2 and to identify factors that could make individuals vulnerable to infection due to lack of response to...
10.
Shi Z, Mori-Akiyama Y, Du W, Fultz R, Zhao Y, Ruan W, et al.
Cell Mol Gastroenterol Hepatol
. 2021 Nov;
13(3):717-737.
PMID: 34781022
Background & Aims: We previously showed that histamine suppressed inflammation-associated colonic tumorigenesis through histamine type 2 receptor (H2R) signaling in mice. This study aimed to precisely elucidate the downstream effects...