Jennifer K Spinler
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Explore the profile of Jennifer K Spinler including associated specialties, affiliations and a list of published articles.
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46
Citations
1201
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Recent Articles
11.
Kellermayer R, Wu Q, Nagy-Szakal D, Queliza K, Ihekweazu F, Bocchini C, et al.
J Pediatr Gastroenterol Nutr
. 2021 Nov;
74(2):227-235.
PMID: 34724447
Objectives: Fecal microbiota transplantation (FMT) is arguably the most effective treatment for recurrent Clostridioides difficile infection (rCDI). Clinical reports on pediatric FMT have not systematically evaluated microbiome restoration in patients...
12.
Luck B, Horvath T, Engevik K, Ruan W, Haidacher S, Hoch K, et al.
Biomolecules
. 2021 Aug;
11(8).
PMID: 34439760
Background: Accumulating evidence indicates that the gut microbiota can synthesize neurotransmitters as well as impact host-derived neurotransmitter levels. In the past, it has been challenging to decipher which microbes influence...
13.
Gonzales-Luna A, Spinler J, Oezguen N, Wadud Khan M, Danhof H, Endres B, et al.
Anaerobe
. 2021 May;
70:102387.
PMID: 34044101
Background: Fecal microbiota transplantation (FMT) aims to cure Clostridioides difficile infection (CDI) through reestablishing a healthy microbiome and restoring colonization resistance. Although often effective after one infusion, patients with continued...
14.
Engevik M, Danhof H, Hall A, Engevik K, Horvath T, Haidacher S, et al.
BMC Microbiol
. 2021 May;
21(1):154.
PMID: 34030655
Background: Bifidobacteria are commensal microbes of the mammalian gastrointestinal tract. In this study, we aimed to identify the intestinal colonization mechanisms and key metabolic pathways implemented by Bifidobacterium dentium. Results:...
15.
Engevik M, Herrmann B, Ruan W, Engevik A, Engevik K, Ihekweazu F, et al.
Gut Microbes
. 2021 May;
13(1):1-21.
PMID: 33985416
Endoplasmic reticulum (ER) stress compromises the secretion of MUC2 from goblet cells and has been linked with inflammatory bowel disease (IBD). Although can beneficially modulate mucin production, little work has...
16.
Marquez L, Koy T, Spinler J, Luna R, Tocco L, Fasciano L, et al.
Infect Control Hosp Epidemiol
. 2021 May;
43(8):1088-1090.
PMID: 33934744
No abstract available.
17.
Engevik M, Danhof H, Ruan W, Engevik A, Chang-Graham A, Engevik K, et al.
mBio
. 2021 Mar;
12(2).
PMID: 33653893
Multiple studies have implicated microbes in the development of inflammation, but the mechanisms remain unknown. Bacteria in the genus have been identified in the intestinal mucosa of patients with digestive...
18.
Spinler J, Oezguen N, Runge J, Luna R, Karri V, Yang J, et al.
ExRNA
. 2021 Feb;
2.
PMID: 33542959
Background: Global estimations of 4 billion people living on plant-based diets signify tremendous diversity in plant consumption and their assorted miRNAs, which presents a challenging model to experimentally address how...
19.
Ihekweazu F, Engevik M, Ruan W, Shi Z, Fultz R, Engevik K, et al.
Am J Pathol
. 2021 Jan;
191(4):704-719.
PMID: 33516788
The intestinal microbiota influences the development and function of the mucosal immune system. However, the exact mechanisms by which commensal microbes modulate immunity is not clear. We previously demonstrated that...
20.
Engevik M, Engevik A, Engevik K, Auchtung J, Chang-Graham A, Ruan W, et al.
ACS Infect Dis
. 2020 Nov;
7(5):1126-1142.
PMID: 33176423
It is widely accepted that the pathogen exploits an intestinal environment with an altered microbiota, but the details of these microbe-microbe interactions are unclear. Adherence and colonization of mucus has...