Jennifer A Beckstead
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Explore the profile of Jennifer A Beckstead including associated specialties, affiliations and a list of published articles.
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21
Citations
431
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Recent Articles
1.
Bratkowski M, Burdett T, Danao J, Wang X, Mathur P, Gu W, et al.
Neuron
. 2022 Sep;
110(22):3711-3726.e16.
PMID: 36087583
Axon degeneration is an early pathological event in many neurological diseases. The identification of the nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 as a central metabolic sensor and axon executioner presents...
2.
Ikon N, Shearer J, Liu J, Tran J, Feng S, Kamei A, et al.
Protein Expr Purif
. 2017 Mar;
134:18-24.
PMID: 28336201
Apolipoprotein (apo) A-I is the major protein component of high-density lipoprotein (HDL) and plays key roles in the Reverse Cholesterol Transport pathway. In the past decade, reconstituted HDL (rHDL) has...
3.
Crosby N, Ghosh M, Su B, Beckstead J, Kamei A, Simonsen J, et al.
Biochem Cell Biol
. 2015 May;
93(4):343-50.
PMID: 25994015
A fusion protein comprising an α-CD20 single chain variable fragment (scFv) antibody, a spacer peptide, and human apolipoprotein (apo) A-I was constructed and expressed in Escherichia coli. The lipid interaction...
4.
Witkowski A, Krishnamoorthy A, Su B, Beckstead J, Ryan R
Protein Expr Purif
. 2014 Dec;
106:41-8.
PMID: 25448592
Wnt proteins are a family of morphogens that possess potent biological activity. Structure-function studies have been impeded by poor yield of biologically active recombinant Wnt as well as a propensity...
5.
Sharma V, Witkowski A, Witkowska H, Dykstra A, Simonsen J, Nelbach L, et al.
Arterioscler Thromb Vasc Biol
. 2014 Aug;
34(10):2254-60.
PMID: 25127531
Objective: Apolipoprotein A-V (apoA-V) is a low-abundance plasma protein that modulates triacylglycerol homeostasis. Gene transfer studies were undertaken in apoa5 (-/-) mice to define the mechanism underlying the correlation between...
6.
Sharma V, Beckstead J, Simonsen J, Nelbach L, Watson G, Forte T, et al.
Arterioscler Thromb Vasc Biol
. 2013 Jan;
33(3):474-80.
PMID: 23329134
Objective: Apolipoprotein (apo) A-V is a low abundance protein with a profound influence on plasma triacylglycerol levels. In human populations, single nucleotide polymorphisms and mutations in APOA5 positively correlate with...
7.
Ma C, Beckstead J, Thompson A, Hafiane A, Leo Wang R, Ryan R, et al.
Biochem Cell Biol
. 2012 May;
90(5):636-45.
PMID: 22607224
Mechanisms to increase plasma high-density lipoprotein (HDL) or to promote egress of cholesterol from cholesterol-loaded cells (e.g., foam cells from atherosclerotic lesions) remain an important target to regress heart disease....
8.
Kamei A, Hauser P, Beckstead J, Weers P, Ryan R
Protein Expr Purif
. 2012 Apr;
83(2):113-6.
PMID: 22487214
Expressed protein ligation (EPL) was performed to investigate sequence requirements for a variant human apolipoprotein A-I (apoA-I) to adopt a folded structure. A C-terminal truncated apoA-I, corresponding to residues 1-172,...
9.
Perez-de-Luque A, Cifuentes Z, Beckstead J, Sillero J, Avila C, Rubio J, et al.
Pest Manag Sci
. 2011 Jun;
68(1):67-74.
PMID: 21710554
Background: The development of water-soluble nanodevices extends the potential use of compounds developed for other purposes (e.g. antifungal drugs or antibiotics) for applications in agriculture. For example, the broad-spectrum, water-insoluble,...
10.
Shu X, Nelbach L, Weinstein M, Burgess B, Beckstead J, Young S, et al.
Arterioscler Thromb Vasc Biol
. 2010 Oct;
30(12):2504-9.
PMID: 20966404
Objective: Apolipoprotein A-V (apoA-V), a minor protein associated with lipoproteins, has a major effect on triacylglycerol (TG) metabolism. We investigated whether apoA-V complexed with phospholipid in the form of a...