Jen-Hsing Shih
Overview
Explore the profile of Jen-Hsing Shih including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
152
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0
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Recent Articles
1.
Oh J, Przepiorski A, Chang H, Dodd R, Sander V, Sorrenson B, et al.
J R Soc N Z
. 2024 Oct;
52(1):54-67.
PMID: 39440007
We aimed to generate human induced pluripotent stem cell (iPSC) lines from New Zealand donors. These lines are the first to be generated in New Zealand. Human dermal fibroblasts were...
2.
Tran K, Kolekar S, Wang Q, Shih J, Buchanan C, Deva S, et al.
Mol Cancer Ther
. 2022 Oct;
21(12):1777-1787.
PMID: 36198029
The fact that 10% of colorectal cancer tumors harbor BRAF V600E mutations suggested targeting BRAF as a potential therapy. However, BRAF inhibitors have only limited single-agent efficacy in this context....
3.
Tran K, Kolekar S, Jabed A, Jaynes P, Shih J, Wang Q, et al.
BMC Cancer
. 2021 Feb;
21(1):136.
PMID: 33549048
Background: The PI 3-kinase (PI3K) pathway has been implicated as a target for melanoma therapy. Methods: Given the high degree of genetic heterogeneity in melanoma, we sought to understand the...
4.
Tran K, Gimenez G, Tsai P, Kolekar S, Rodger E, Chatterjee A, et al.
Pigment Cell Melanoma Res
. 2020 Jun;
34(1):136-143.
PMID: 32567790
Melanoma is a disease associated with a very high mutation burden and thus the possibility of a diverse range of oncogenic mechanisms that allow it to evade therapeutic interventions and...
5.
Przepiorski A, Sander V, Tran T, Hollywood J, Sorrenson B, Shih J, et al.
Stem Cell Reports
. 2018 Jul;
11(2):470-484.
PMID: 30033089
Kidney organoids made from pluripotent stem cells have the potential to revolutionize how kidney development, disease, and injury are studied. Current protocols are technically complex, suffer from poor reproducibility, and...
6.
Buchanan C, Shih J, Astin J, Rewcastle G, Flanagan J, Crosier P, et al.
Clin Sci (Lond)
. 2011 Dec;
122(10):449-57.
PMID: 22142330
The flavone acetic acid derivative DMXAA [5,6-dimethylXAA (xanthenone-4-acetic acid), Vadimezan, ASA404] is a drug that displayed vascular-disrupting activity and induced haemorrhagic necrosis and tumour regression in pre-clinical animal models. Both...