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Jeffrey W Schmidt

Explore the profile of Jeffrey W Schmidt including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 148
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Recent Articles
1.
Sakamoto K, Schmidt J, Wagner K
Methods Mol Biol . 2015 Feb; 1267:47-71. PMID: 25636464
Breast cancer is the most common cause of cancer death in women worldwide. This malignancy is a complex disease, which is defined by an intrinsic heterogeneity on the histopathological and...
2.
Schmidt J, Wehde B, Sakamoto K, Triplett A, West W, Wagner K
BMC Cancer . 2014 Mar; 14:195. PMID: 24628780
Background: The serine-threonine kinase AKT1 plays essential roles during normal mammary gland development as well as the initiation and progression of breast cancer. AKT1 is generally considered a ubiquitously expressed...
3.
Schmidt J, Wehde B, Sakamoto K, Triplett A, Anderson S, Tsichlis P, et al.
Mol Cell Biol . 2014 Jan; 34(7):1363-77. PMID: 24469394
Stat5 (signal transducer and activator of transcription 5) is an essential mediator of cytokine receptor signaling and plays important roles in the proliferation of alveolar progenitors and the survival of...
4.
Lin W, Schmidt J, Creamer B, Triplett A, Wagner K
PLoS One . 2013 Apr; 8(4):e60902. PMID: 23565285
The Signal Transducer and Activator of Transcription 5 (Stat5) plays a significant role in normal hematopoiesis and a variety of hematopoietic malignancies. Deficiency in Stat5 causes impaired cytokine-mediated proliferation and...
5.
Sakamoto K, Schmidt J, Wagner K
PLoS One . 2012 Sep; 7(8):e43778. PMID: 22952764
We have generated a new and improved transgenic mouse strain that permits a temporally controlled expression of transgenes throughout mammary gland development. High expression of the tetracycline-regulatible transactivator (tTA) under...
6.
Wagner K, Schmidt J
J Carcinog . 2012 Jan; 10:32. PMID: 22279417
Since its discovery as "just another kinase" more than twenty years ago, the family of JAK tyrosine kinases and their respective Signal Transducers and Activators of Transcription (STATs) has been...
7.
Creamer B, Sakamoto K, Schmidt J, Triplett A, Moriggl R, Wagner K
Mol Cell Biol . 2010 Apr; 30(12):2957-70. PMID: 20385773
The signal transducer and activator of transcription 5 (Stat5) plays a pivotal role in the proliferation, secretory differentiation, and survival of mammary epithelial cells. However, there is little information about...