Jeffrey VanWye
Overview
Explore the profile of Jeffrey VanWye including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
161
Followers
0
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Recent Articles
1.
Wickramage I, VanWye J, Max K, Lockhart J, Hortu I, Mong E, et al.
Cell Host Microbe
. 2024 Oct;
32(11):2035.
PMID: 39396520
No abstract available.
2.
Wickramage I, VanWye J, Max K, Lockhart J, Hortu I, Mong E, et al.
Cell Host Microbe
. 2023 Jun;
31(7):1185-1199.e10.
PMID: 37315561
Hemochorial placentas have evolved defense mechanisms to prevent the vertical transmission of viruses to the immunologically underdeveloped fetus. Unlike somatic cells that require pathogen-associated molecular patterns to stimulate interferon production,...
3.
Lockhart J, VanWye J, Banerjee R, Wickline S, Pan H, Totary-Jain H
Mol Ther
. 2021 Feb;
29(5):1744-1757.
PMID: 33545360
Cardiovascular disease is the leading cause of death and disability worldwide. Effective delivery of cell-selective therapies that target atherosclerotic plaques and neointimal growth while sparing the endothelium remains the Achilles...
4.
Mong E, Yang Y, Akat K, Canfield J, VanWye J, Lockhart J, et al.
Sci Rep
. 2020 Feb;
10(1):3029.
PMID: 32080251
During implantation, cytotrophoblasts undergo epithelial-to-mesenchymal transition (EMT) as they differentiate into invasive extravillous trophoblasts (EVTs). The primate-specific microRNA cluster on chromosome 19 (C19MC) is exclusively expressed in the placenta, embryonic...
5.
Lockhart J, Canfield J, Mong E, VanWye J, Totary-Jain H
Mol Ther Nucleic Acids
. 2019 Jan;
14:339-350.
PMID: 30665183
mRNA therapeutics hold great promise for the treatment of human diseases. While incorporating naturally occurring modified nucleotides during synthesis has greatly increased their potency and safety, challenges in selective expression...
6.
Canfield J, Arlier S, Mong E, Lockhart J, VanWye J, Guzeloglu-Kayisli O, et al.
FASEB J
. 2018 Oct;
33(2):2759-2769.
PMID: 30307771
Preeclampsia (PE) is a common cause of maternal morbidity, characterized by impaired trophoblast invasion and spiral artery transformation resulting in progressive uteroplacental hypoxia. Given the primary role of LIN28A and...
7.
Mong E, Akat K, Canfield J, Lockhart J, VanWye J, Matar A, et al.
Arterioscler Thromb Vasc Biol
. 2018 May;
38(6):1321-1332.
PMID: 29724816
Objective: Infantile hemangiomas (IHs) are the most common benign vascular neoplasms of infancy, characterized by a rapid growth phase followed by a spontaneous involution, or triggered by propranolol treatment by...
8.
Astudillo L, Da Silva T, Wang Z, Han X, Jin K, VanWye J, et al.
Cancer Res
. 2016 May;
76(12):3593-603.
PMID: 27197169
In many cancers, aberrant Notch activity has been demonstrated to play a role in the initiation and maintenance of the neoplastic phenotype and in cancer stem cells, which may allude...