John Lockhart
Overview
Explore the profile of John Lockhart including associated specialties, affiliations and a list of published articles.
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9
Citations
118
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0
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Recent Articles
1.
Anderson K, Bompadre V, Parker C, Varakitsomboon S, Krengel 3rd W, Lockhart J, et al.
J Pediatr Orthop
. 2022 Feb;
42(4):e367-e372.
PMID: 35125413
Background: To minimize in-person visits during the COVID-19 pandemic, a new fracture care protocol for children with complete and stable, nondisplaced or minimally displaced upper extremity (UE) fractures has been...
2.
Mong E, Yang Y, Akat K, Canfield J, VanWye J, Lockhart J, et al.
Sci Rep
. 2020 Feb;
10(1):3029.
PMID: 32080251
During implantation, cytotrophoblasts undergo epithelial-to-mesenchymal transition (EMT) as they differentiate into invasive extravillous trophoblasts (EVTs). The primate-specific microRNA cluster on chromosome 19 (C19MC) is exclusively expressed in the placenta, embryonic...
3.
Marin de Evsikova C, Raplee I, Lockhart J, Jaimes G, Evsikov A
J Pers Med
. 2019 Apr;
9(2).
PMID: 31032818
As one of the most widespread metabolic diseases, atherosclerosis affects nearly everyone as they age; arteries gradually narrow from plaque accumulation over time reducing oxygenated blood flow to central and...
4.
Lockhart J, Canfield J, Mong E, VanWye J, Totary-Jain H
Mol Ther Nucleic Acids
. 2019 Jan;
14:339-350.
PMID: 30665183
mRNA therapeutics hold great promise for the treatment of human diseases. While incorporating naturally occurring modified nucleotides during synthesis has greatly increased their potency and safety, challenges in selective expression...
5.
Canfield J, Arlier S, Mong E, Lockhart J, VanWye J, Guzeloglu-Kayisli O, et al.
FASEB J
. 2018 Oct;
33(2):2759-2769.
PMID: 30307771
Preeclampsia (PE) is a common cause of maternal morbidity, characterized by impaired trophoblast invasion and spiral artery transformation resulting in progressive uteroplacental hypoxia. Given the primary role of LIN28A and...
6.
Mong E, Akat K, Canfield J, Lockhart J, VanWye J, Matar A, et al.
Arterioscler Thromb Vasc Biol
. 2018 May;
38(6):1321-1332.
PMID: 29724816
Objective: Infantile hemangiomas (IHs) are the most common benign vascular neoplasms of infancy, characterized by a rapid growth phase followed by a spontaneous involution, or triggered by propranolol treatment by...
7.
Wilkinson D, Desilets A, Lin H, Charlton S, Arques M, Falconer A, et al.
Sci Rep
. 2017 Dec;
7(1):16693.
PMID: 29196708
Increasing evidence implicates serine proteinases in the proteolytic cascades leading to the pathological destruction of extracellular matrices such as cartilage in osteoarthritis (OA). We have previously demonstrated that the type...
8.
McIntosh K, Cunningham M, Cadalbert L, Lockhart J, Boyd G, Ferrell W, et al.
Cell Signal
. 2009 Sep;
22(2):265-73.
PMID: 19781631
In this study we examined the potential for PAR(2) and TNFalpha to synergise at the level of MAP kinase signalling in PAR(2) expressing NCTC2544 cells. However, to our surprise we...
9.
Ferrell W, Kelso E, Lockhart J, Dunning L
Arthritis Rheum
. 2007 Oct;
56(10):3510.
PMID: 17907181
No abstract available.