Jeffrey S Taylor
Overview
Explore the profile of Jeffrey S Taylor including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
247
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0
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Recent Articles
1.
Little K, Taylor J, Schlosser M
Healthc Financ Manage
. 2018 Jun;
70(11):88-84.
PMID: 29897221
No abstract available.
2.
Brown R, Tan D, Taylor J, Miller M, Prichard J, Kott M
Ann Clin Lab Sci
. 2007 May;
37(2):141-7.
PMID: 17522369
Morphoproteomic analysis reveals the constitutive activation of the mTOR, ERK, and NF-kappaB pathways in high risk neuroblastoma (HRN) cases as evidenced by (a) collective commonalities of: phosphorylated (p)-mTOR, p70S6K, ERK...
3.
Taylor J, Reid T, Terry K, Casey P, Beese L
EMBO J
. 2003 Nov;
22(22):5963-74.
PMID: 14609943
Protein geranylgeranyltransferase type-I (GGTase-I), one of two CaaX prenyltransferases, is an essential enzyme in eukaryotes. GGTase-I catalyzes C-terminal lipidation of >100 proteins, including many GTP- binding regulatory proteins. We present...
4.
deSolms S, Ciccarone T, MacTough S, Shaw A, Buser C, Ellis-Hutchings M, et al.
J Med Chem
. 2003 Jun;
46(14):2973-84.
PMID: 12825937
A series of novel diaryl ether lactams have been identified as very potent dual inhibitors of protein farnesyltransferase (FTase) and protein geranylgeranyltransferase I (GGTase-I), enzymes involved in the prenylation of...
5.
Johnson S, Taylor J, Beese L
Proc Natl Acad Sci U S A
. 2003 Mar;
100(7):3895-900.
PMID: 12649320
DNA polymerases replicate DNA by adding nucleotides to a growing primer strand while avoiding frameshift and point mutations. Here we present a series of up to six successive replication events...
6.
Bell I, Gallicchio S, Abrams M, Beese L, Beshore D, Bhimnathwala H, et al.
J Med Chem
. 2002 May;
45(12):2388-409.
PMID: 12036349
A series of macrocyclic 3-aminopyrrolidinone farnesyltransferase inhibitors (FTIs) has been synthesized. Compared with previously described linear 3-aminopyrrolidinone FTIs such as compound 1, macrocycles such as 49 combined improved pharmacokinetic properties...