Jeffrey R Moffitt
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Explore the profile of Jeffrey R Moffitt including associated specialties, affiliations and a list of published articles.
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54
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4763
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Recent Articles
1.
Cadinu P, Yang E, Xu R, Watson B, Luce J, Moffitt J
Curr Protoc
. 2025 Mar;
5(3):e70111.
PMID: 40029168
Multiplexed error-robust fluorescence in situ hybridization (MERFISH) is a massively multiplexed single RNA-molecule imaging technique capable of spatially resolved single-cell transcriptomic profiling of thousands of genes in millions of cells...
2.
Moffitt J, Li M, Nie Q, Kanemaru K, Teichmann S, Dar D, et al.
Cell Syst
. 2025 Feb;
16(2):101200.
PMID: 39978311
No abstract available.
3.
Sarfatis A, Wang Y, Twumasi-Ankrah N, Moffitt J
Science
. 2025 Jan;
387(6732):eadr0932.
PMID: 39847624
Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hindered by the massive density...
4.
Watson B, Paul B, Rahman R, Amir-Zilberstein L, Segerstolpe A, Epstein E, et al.
Nat Commun
. 2025 Jan;
16(1):319.
PMID: 39747812
Single-cell RNA sequencing (scRNA-seq) has advanced our understanding of cell types and their heterogeneity within the human liver, but the spatial organization at single-cell resolution has not yet been described....
5.
Nicol P, Ma R, Xu R, Moffitt J, Irizarry R
bioRxiv
. 2024 Nov;
PMID: 39605709
Spatial transcriptomics enables high-resolution gene expression measurements while preserving the two-dimensional spatial organization of the sample. A common objective in spatial transcriptomics data analysis is to identify spatially variable genes...
6.
Sarfatis A, Wang Y, Twumasi-Ankrah N, Moffitt J
bioRxiv
. 2024 Jul;
PMID: 38979245
Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hindered by the massive density...
7.
Laubscher E, Wang X, Razin N, Dougherty T, Xu R, Ombelets L, et al.
Cell Syst
. 2024 May;
15(5):475-482.e6.
PMID: 38754367
Image-based spatial transcriptomics methods enable transcriptome-scale gene expression measurements with spatial information but require complex, manually tuned analysis pipelines. We present Polaris, an analysis pipeline for image-based spatial transcriptomics that...
8.
Cadinu P, Sivanathan K, Misra A, Xu R, Mangani D, Yang E, et al.
Cell
. 2024 Apr;
187(8):2010-2028.e30.
PMID: 38569542
Gut inflammation involves contributions from immune and non-immune cells, whose interactions are shaped by the spatial organization of the healthy gut and its remodeling during inflammation. The crosstalk between fibroblasts...
9.
Wu M, Zheng W, Song X, Bao B, Wang Y, Ramanan D, et al.
Cell
. 2024 Jan;
187(4):897-913.e18.
PMID: 38280374
Canonically, the complement system is known for its rapid response to remove microbes in the bloodstream. However, relatively little is known about a functioning complement system on intestinal mucosal surfaces....
10.
Aw E, Zhang Y, Yalcin E, Herrmann U, Lin S, Langston K, et al.
Brain Behav Immun
. 2023 Dec;
116:419.
PMID: 38065810
No abstract available.