Jeffrey O Spector
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Explore the profile of Jeffrey O Spector including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
274
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Recent Articles
1.
Spector J, Chen J, Szczesna E, Roll-Mecak A
J Microsc
. 2024 Dec;
298(1):10-16.
PMID: 39629928
Interference Reflection Microscopy (IRM) is an optical technique that relies on the interference between the reflected light from an incident beam as it passes through materials of different refractive indices....
2.
Spector J, Chen J, Roll-Mecak A
bioRxiv
. 2024 Oct;
PMID: 39372801
Interference Reflection Microscopy (IRM) is an optical technique that relies on the interference between the reflected light from an incident beam as it passes through materials of different refractive indices....
3.
Spector J, Vemu A, Roll-Mecak A
Methods Mol Biol
. 2019 Dec;
2101:39-51.
PMID: 31879897
Microtubules are dynamic non-covalent mesoscopic polymers. Their dynamic behavior is essential for cell biological processes ranging from intracellular transport to cell division and neurogenesis. Fluorescence microscopy has been the method...
4.
Vemu A, Szczesna E, Zehr E, Spector J, Grigorieff N, Deaconescu A, et al.
Science
. 2018 Aug;
361(6404).
PMID: 30139843
Spastin and katanin sever and destabilize microtubules. Paradoxically, despite their destructive activity they increase microtubule mass in vivo. We combined single-molecule total internal reflection fluorescence microscopy and electron microscopy to...
5.
Vemu A, Atherton J, Spector J, Moores C, Roll-Mecak A
Mol Biol Cell
. 2017 Oct;
28(25):3564-3572.
PMID: 29021343
Microtubules polymerize and depolymerize stochastically, a behavior essential for cell division, motility, and differentiation. While many studies advanced our understanding of how microtubule-associated proteins tune microtubule dynamics in trans, we...
6.
Vemu A, Atherton J, Spector J, Szyk A, Moores C, Roll-Mecak A
J Biol Chem
. 2016 Apr;
291(25):12907-15.
PMID: 27129203
Microtubules are polymers that cycle stochastically between polymerization and depolymerization, i.e. they exhibit "dynamic instability." This behavior is crucial for cell division, motility, and differentiation. Although studies in the last...