Jeffrey K Huang
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Explore the profile of Jeffrey K Huang including associated specialties, affiliations and a list of published articles.
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42
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1144
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Recent Articles
1.
Nanescu S, Wathieu N, Rosko L, Cha D, Kumar M, Olszewski R, et al.
Front Cell Neurosci
. 2025 Mar;
19:1550139.
PMID: 40065911
Myelin regeneration (remyelination) in the CNS depends on the recruitment, proliferation and differentiation of oligodendrocyte precursor cells (OPCs) at demyelinated lesions. However, despite the presence of OPCs, very few oligodendrocytes...
2.
Gross P, Duran-Laforet V, Ho L, Melchor G, Zia S, Manavi Z, et al.
Nat Commun
. 2025 Mar;
16(1):2283.
PMID: 40055369
The capacity to regenerate myelin in the central nervous system diminishes with age. This decline is particularly evident in multiple sclerosis (MS), a chronic demyelinating disease. Whether cellular senescence, a...
3.
Gharibani P, Abramson E, Shanmukha S, Smith M, Godfrey W, Lee J, et al.
Sci Transl Med
. 2025 Jan;
17(780):eadk3434.
PMID: 39772770
In multiple sclerosis (MS), microglia and macrophages within the central nervous system (CNS) play an important role in determining the balance among demyelination, neurodegeneration, and myelin repair. Phagocytic and regenerative...
4.
Melchor G, Baydyuk M, Manavi Z, Hu J, Huang J
bioRxiv
. 2025 Jan;
PMID: 39764038
Demyelination, or the loss of myelin in the central nervous system (CNS) is a hallmark of multiple sclerosis (MS) and occurs in various forms of CNS injury and neurodegenerative diseases....
5.
Majumder P, Hsu T, Hu C, Huang J, Lee Y, Hsieh Y, et al.
Exp Neurol
. 2024 Oct;
383:114999.
PMID: 39419433
Background: Amyotrophic lateral sclerosis (ALS) was first identified in 1869, but it wasn't until the 2014 Ice Bucket Challenge that widespread attention was drawn to the disease. Since then, substantial...
6.
Gross P, Laforet V, Manavi Z, Zia S, Lee S, Shults N, et al.
bioRxiv
. 2024 Jun;
PMID: 38826296
The capacity to regenerate myelin in the central nervous system (CNS) diminishes with age. This decline is particularly evident in multiple sclerosis (MS), which has been suggested to exhibit features...
7.
Hu J, Melchor G, Ladakis D, Reger J, Kim H, Chamberlain K, et al.
NPJ Regen Med
. 2024 Jan;
9(1):1.
PMID: 38167866
Regulation of myeloid cell activity is critical for successful myelin regeneration (remyelination) in demyelinating diseases, such as multiple sclerosis (MS). Here, we show aromatic alpha-keto acids (AKAs) generated from the...
8.
Demby T, Gross P, Mandelblatt J, Huang J, Rebeck G
Exp Neurol
. 2023 Nov;
371:114609.
PMID: 37944881
Many cancer patients experience serious cognitive problems related to their treatment, which can greatly affect their quality of life. The molecular mechanisms of this cancer chemotherapy-induced cognitive impairment (CICI) are...
9.
Gharibani P, Abramson E, Shanmukha S, Smith M, Godfrey W, Lee J, et al.
bioRxiv
. 2023 Sep;
PMID: 37693473
In multiple sclerosis (MS), microglia and macrophages within the central nervous system (CNS) play an important role in determining the balance between myelin repair and demyelination/neurodegeneration. Phagocytic and regenerative functions...
10.
Donovan A, Rosko L, Ellegood J, Redhead Y, Green J, Lerch J, et al.
J Anat
. 2023 Mar;
243(1):51-65.
PMID: 36914558
CHARGE (Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth, Genital anomalies and Ear abnormalities) syndrome is a disorder caused by mutations in the gene encoding...