Jeffrey J Tabor
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Explore the profile of Jeffrey J Tabor including associated specialties, affiliations and a list of published articles.
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47
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1674
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Recent Articles
1.
Haller D, Castillo-Hair S, Tabor J
Methods Mol Biol
. 2024 Dec;
2840:1-17.
PMID: 39724340
Optogenetics enables precise control of gene expression in a variety of organisms. We recently developed the first system for optogenetic control of transcription in Bacillus subtilis. This system is based...
2.
Aghlara-Fotovat S, Musteata E, Doerfert M, Baruch M, Levitan M, Tabor J, et al.
Biomaterials
. 2023 Jul;
301:122246.
PMID: 37481834
Bacteria can be genetically programmed to sense and report the presence of disease biomarkers in the gastrointestinal (GI) tract. However, diagnostic bacteria are typically delivered via oral administration of liquid...
3.
Brink K, Hunt M, Mu A, Groszman K, Hoang K, Lorch K, et al.
Nat Chem Biol
. 2022 Dec;
19(4):451-459.
PMID: 36482094
Bacteria use two-component system (TCS) signaling pathways to sense and respond to peptides involved in host defense, quorum sensing and inter-bacterial warfare. However, little is known about the broad peptide-sensing...
4.
Butcher R, Tabor J
Proc Natl Acad Sci U S A
. 2022 Aug;
119(35):e2201204119.
PMID: 35994658
Bacteria utilize two-component system (TCS) signal transduction pathways to sense and adapt to changing environments. In a typical TCS, a stimulus induces a sensor histidine kinase (SHK) to phosphorylate a...
5.
Beal J, Teague B, Sexton J, Castillo-Hair S, DeLateur N, Samineni M, et al.
ACS Synth Biol
. 2022 Feb;
11(3):1196-1207.
PMID: 35156365
Reliable, predictable engineering of cellular behavior is one of the key goals of synthetic biology. As the field matures, biological engineers will become increasingly reliant on computer models that allow...
6.
Lazar J, Tabor J
Curr Opin Syst Biol
. 2021 Dec;
28.
PMID: 34917859
Two-component systems (TCSs) are a ubiquitous family of signal transduction pathways that enable bacteria to sense and respond to diverse physical, chemical, and biological stimuli outside and inside the cell....
7.
Gerhardt K, Rao S, Olson E, Igoshin O, Tabor J
Nat Commun
. 2021 Nov;
12(1):6957.
PMID: 34845228
Gene expression noise can reduce cellular fitness or facilitate processes such as alternative metabolism, antibiotic resistance, and differentiation. Unfortunately, efforts to study the impacts of noise have been hampered by...
8.
Baig H, Fontanarossa P, Kulkarni V, McLaughlin J, Vaidyanathan P, Bartley B, et al.
J Integr Bioinform
. 2021 Jun;
18(3).
PMID: 34098590
People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the...
9.
Cartwright I, Dowdell A, Lanis J, Brink K, Mu A, Kostelecky R, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(20).
PMID: 33972436
Metabolic changes associated with tissue inflammation result in significant extracellular acidosis (EA). Within mucosal tissues, intestinal epithelial cells (IEC) have evolved adaptive strategies to cope with EA through the up-regulation...
10.
Hartsough L, Park M, Kotlajich M, Lazar J, Han B, Lin C, et al.
Elife
. 2020 Dec;
9.
PMID: 33325823
Gut microbial metabolism is associated with host longevity. However, because it requires direct manipulation of microbial metabolism in situ, establishing a causal link between these two processes remains challenging. We...