Jeffrey J Landers
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Explore the profile of Jeffrey J Landers including associated specialties, affiliations and a list of published articles.
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26
Citations
379
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Recent Articles
11.
Baker Jr J, Rasky A, Landers J, Janczak K, Totten T, Lukacs N, et al.
Clin Exp Allergy
. 2021 May;
51(10):1361-1373.
PMID: 33999457
Background: Atopic diseases are an increasing problem that involve both immediate hypersensitivity reactions mediated by IgE and unique cellular inflammation. Many forms of specific immunotherapy involve the administration of allergen...
12.
Farazuddin M, Landers J, Janczak K, Lindsey H, Finkelman F, Baker Jr J, et al.
Front Immunol
. 2021 Mar;
12:599296.
PMID: 33717078
We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection...
13.
Jangra S, Landers J, Rathnasinghe R, OKonek J, Janczak K, Cascalho M, et al.
bioRxiv
. 2021 Feb;
PMID: 33619480
Several SARS-CoV-2 vaccines have received EUAs, but many issues remain unresolved, including duration of conferred immunity and breadth of cross-protection. Adjuvants that enhance and shape adaptive immune responses that confer...
14.
Wong P, Goff P, Sun R, Ruge M, Ermler M, Sebring A, et al.
Mol Pharm
. 2020 Jun;
18(2):679-698.
PMID: 32491861
Current influenza virus vaccines are focused on humoral immunity and are limited by the short duration of protection, narrow cross-strain efficacy, and suboptimal immunogenicity. Here, we combined two chemically and...
15.
OKonek J, Landers J, Janczak K, Lindsey H, Mondrusov A, Totten T, et al.
Allergy
. 2019 Sep;
75(4):872-881.
PMID: 31557317
Background: Immunotherapy for food allergy requires prolonged treatment protocols and, in most cases, does not lead to durable modulation of the allergic immune response. We have demonstrated an intranasal (IN)...
16.
Farazuddin M, Goel R, Kline N, Landers J, OKonek J, Baker Jr J
Front Immunol
. 2019 May;
10:916.
PMID: 31134057
Mucosal surfaces are the primary point of entry for many infectious agents and mucosal immune responses serve as the primary defense to these pathogens. In order to mount an effective...
17.
OKonek J, Landers J, Janczak K, Goel R, Mondrusov A, Wong P, et al.
J Allergy Clin Immunol
. 2018 Apr;
141(6):2121-2131.
PMID: 29655584
Background: Immunotherapy for food allergies involves progressive increased exposures to food that result in desensitization to food allergens in some subjects but not tolerance to the food. Therefore new approaches...
18.
OKonek J, Makidon P, Landers J, Cao Z, Malinczak C, Pannu J, et al.
Hum Vaccin Immunother
. 2015 Aug;
11(12):2904-12.
PMID: 26307915
Respiratory Syncytial Virus is a leading cause of bronchiolitis and pneumonia in infants, the elderly and individuals with compromised immune systems. Despite decades of research, there is currently no available...
19.
Sitrin R, Sassanella T, Landers J, Petty H
Am J Respir Cell Mol Biol
. 2009 Nov;
43(4):498-506.
PMID: 19933376
Highly ordered sphingolipid-enriched lipid raft microdomains (LRMs) within plasma membranes purportedly function as specialized signaling platforms. Leukocyte migration is believed to entail LRM redistribution, but progress in studying LRMs in...
20.
Makidon P, Bielinska A, Nigavekar S, Janczak K, Knowlton J, Scott A, et al.
PLoS One
. 2008 Aug;
3(8):e2954.
PMID: 18698426
Background: Hepatitis B virus infection remains an important global health concern despite the availability of safe and effective prophylactic vaccines. Limitations to these vaccines include requirement for refrigeration and three...