Mohammad Farazuddin
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Explore the profile of Mohammad Farazuddin including associated specialties, affiliations and a list of published articles.
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20
Citations
190
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Recent Articles
1.
Laghlali G, Wiest M, Karadag D, Warang P, OKonek J, Chang L, et al.
Mol Ther
. 2024 Nov;
32(12):4448-4466.
PMID: 39489918
Current COVID-19 mRNA vaccines delivered intramuscularly (IM) induce effective systemic immunity, but with suboptimal immunity at mucosal sites, limiting their ability to impart sterilizing immunity. There is strong interest in...
2.
Farazuddin M, Acker G, Zourob J, OKonek J, Wong P, Morris S, et al.
iScience
. 2024 Jul;
27(7):110103.
PMID: 39045100
Retinoic acid (RA), controls the immunoregulatory functions of many immune cells, including dendritic cells (DCs), and is important for mucosal immunity. In DCs, RA regulates the expression of pattern recognition...
3.
Laghlali G, Wiest M, Karadag D, Warang P, OKonek J, Chang L, et al.
bioRxiv
. 2024 Apr;
PMID: 38586014
Current COVID-19 mRNA vaccines delivered intramuscularly (IM) induce effective systemic immunity, but with suboptimal immunity at mucosal sites, limiting their ability to impart sterilizing immunity. There is strong interest in...
4.
Wang S, Cao Z, Farazuddin M, Chen J, Janczak K, Tang S, et al.
Cancer Gene Ther
. 2024 Jan;
31(3):464-471.
PMID: 38177307
KRAS mutations occur commonly in the lung and can lead to the development of non-small cell lung cancer (NSCLC). While the mutated KRAS protein is a neoantigen, it usually does...
5.
Tang S, Chen J, Cannon J, Chekuri M, Farazuddin M, Baker Jr J, et al.
Pharmaceutics
. 2023 Jul;
15(7).
PMID: 37514184
The objective of the study was to explore the feasibility of a new drug delivery system using laponite (LAP) and cyclic poly(ethylene glycol) (cPEG). Variously shaped and flexible hybrid nanocrystals...
6.
Farazuddin M, Ludka N, Friesen L, Landers J, OKonek J, Kim C, et al.
Immunohorizons
. 2023 Jun;
7(6):480-492.
PMID: 37341756
Vitamin A and its biologically active metabolites, all-trans and 9-cis retinoic acid (RA), are thought to be important in generating and modulating immune function. However, RA modulates the function of...
7.
Jamal F, Ahmed G, Farazuddin M, Altaf I, Farheen S, Zia Q, et al.
Molecules
. 2023 Mar;
28(5).
PMID: 36903437
Therapeutics, based on small interfering RNA (siRNA), have demonstrated tremendous potential for treating cancer. However, issues such as non-specific targeting, premature degradation, and the intrinsic toxicity of the siRNA, have...
8.
Baker Jr J, Farazuddin M, Wong P, OKonek J
J Allergy Clin Immunol
. 2022 May;
150(1):1-11.
PMID: 35569567
Recent events involving the global coronavirus pandemic have focused attention on vaccination strategies. Although tremendous advances have been made in subcutaneous and intramuscular vaccines during this time, one area that...
9.
Farazuddin M, Landers J, Janczak K, Lindsey H, Finkelman F, Baker Jr J, et al.
Front Immunol
. 2021 Mar;
12:599296.
PMID: 33717078
We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection...
10.
Farazuddin M, Goel R, Kline N, Landers J, OKonek J, Baker Jr J
Front Immunol
. 2019 May;
10:916.
PMID: 31134057
Mucosal surfaces are the primary point of entry for many infectious agents and mucosal immune responses serve as the primary defense to these pathogens. In order to mount an effective...