Jeffrey J Essner
Overview
Explore the profile of Jeffrey J Essner including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
36
Citations
1837
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ming Z, Liu F, Moran H, Lalonde R, Adams M, Restrepo N, et al.
bioRxiv
. 2024 Dec;
PMID: 39677658
Background: The ability to generate endogenous Cre recombinase drivers using CRISPR-Cas9 knock-in technology allows lineage tracing, cell type specific gene studies, and validation of inferred developmental trajectories from phenotypic and...
2.
Campbell C, Calderon R, Pavani G, Cheng X, Barakat R, Snella E, et al.
Nat Commun
. 2024 Sep;
15(1):7787.
PMID: 39242546
Most gene functions have been discovered through phenotypic observations under loss of function experiments that lack temporal control. However, cell signaling relies on limited transcriptional effectors, having to be re-used...
3.
Srivastava R, Davison C, Krull A, Entriken S, Zumbrock A, Cortes Hidalgo M, et al.
Zebrafish
. 2024 Apr;
21(2):162-170.
PMID: 38621214
We have developed a one-credit semester-long research experience for undergraduate students that involves the use of CRISPR/Cas9 to edit genes in zebrafish. The course is available to students at all...
4.
Davison C, Harzman H, Nicholson J, Entriken S, Mobley K, Krull A, et al.
Zebrafish
. 2024 Apr;
21(2):191-197.
PMID: 38621205
Tjp1a and other tight junction and adherens proteins play important roles in cell-cell adhesion, scaffolding, and forming seals between cells in epithelial and endothelial tissues. In this study, we labeled...
5.
Liu F, Kambakam S, Almeida M, Ming Z, Welker J, Wierson W, et al.
Elife
. 2022 Jun;
11.
PMID: 35713402
The ability to regulate gene activity spatially and temporally is essential to investigate cell-type-specific gene function during development and in postembryonic processes and disease models. The Cre/ system has been...
6.
Welker J, Wierson W, Almeida M, Mann C, Torrie M, Ming Z, et al.
Bio Protoc
. 2021 Aug;
11(14):e4100.
PMID: 34395736
Efficient precision genome engineering requires high frequency and specificity of integration at the genomic target site. Multiple design strategies for zebrafish gene targeting have previously been reported with widely varying...
7.
Almeida M, Welker J, Siddiqui S, Luiken J, Ekker S, Clark K, et al.
Sci Rep
. 2021 Jan;
11(1):1732.
PMID: 33462297
We previously reported efficient precision targeted integration of reporter DNA in zebrafish and human cells using CRISPR/Cas9 and short regions of homology. Here, we apply this strategy to isolate zebrafish...
8.
Ichino N, Serres M, Urban R, Urban M, Treichel A, Schaefbauer K, et al.
Elife
. 2020 Aug;
9.
PMID: 32779569
One key bottleneck in understanding the human genome is the relative under-characterization of 90% of protein coding regions. We report a collection of 1200 transgenic zebrafish strains made with the...
9.
Wierson W, Simone B, WareJoncas Z, Mann C, Welker J, Kar B, et al.
CRISPR J
. 2019 Nov;
2(6):417-433.
PMID: 31742435
CRISPR and CRISPR-Cas effector proteins enable the targeting of DNA double-strand breaks to defined loci based on a variable length RNA guide specific to each effector. The guide RNAs are...
10.
Mann C, Martinez-Galvez G, Welker J, Wierson W, Ata H, Almeida M, et al.
Nucleic Acids Res
. 2019 May;
47(W1):W175-W182.
PMID: 31127311
The discovery and development of DNA-editing nucleases (Zinc Finger Nucleases, TALENs, CRISPR/Cas systems) has given scientists the ability to precisely engineer or edit genomes as never before. Several different platforms,...