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Jeffrey D DeMeis

Explore the profile of Jeffrey D DeMeis including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 37
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Recent Articles
1.
DeMeis J, Roberts J, Delcher H, Godang N, Coley A, Brown C, et al.
Nucleic Acids Res . 2024 Dec; 53(2. PMID: 39658038
Several studies have now described instances where G-rich sequences in promoters and enhancers regulate gene expression through forming G-quadruplex (G4) structures. Relatedly, our group recently identified 301 long genomic stretches...
2.
Godang N, Nguyen A, DeMeis J, Paudel S, Campbell N, Barnes K, et al.
MicroPubl Biol . 2024 Dec; 2024. PMID: 39634108
The excision of specific tRNA-derived small RNAs (tsRNAs), yRNA-derived small RNAs (ysRNAs) and ribosomal RNA-derived small RNAs (rsRNAs) is now well established. Several reports have suggested many of these fragments...
3.
Delcher H, DeMeis J, Ghobar N, Godang N, Knight S, Alqudah S, et al.
MicroPubl Biol . 2024 Feb; 2024. PMID: 38312351
SARS-CoV-2 (SC2) has been intensely studied since its emergence. However, the mechanisms of host immune dysregulation triggered by SC2 remain poorly understood. That said, it is well established that many...
4.
Olliff N, Hunt M, Paudel S, Nguyen K, Delcher H, DeMeis J, et al.
MicroPubl Biol . 2023 Sep; 2023. PMID: 37662051
SARS-CoV-2 infection can result in a range of outcomes from asymptomatic/mild disease to severe COVID-19/fatality. In this study, we investigated the differential expression of small noncoding RNAs (sncRNAs) between patient...
5.
Godang N, DeMeis J, Houserova D, Chaudhary N, Salter C, Xi Y, et al.
MicroPubl Biol . 2023 Feb; 2023. PMID: 36818311
SnoRNAs are frequently processed into snoRNA-derived RNAs (sdRNAs) that function much like traditional microRNAs (miRNAs). That said, our analyses suggest a global switch from DICER-dependent (predominately miRNA) to DICER-independent (predominately...
6.
Coley A, Stahly A, Kasukurthi M, Barchie A, Hutcheson S, Houserova D, et al.
Cells . 2022 Apr; 11(8). PMID: 35455981
We have identified 38 specifically excised, differentially expressed snoRNA fragments (sdRNAs) in TCGA prostate cancer (PCa) patient samples as compared to normal prostate controls. SnoRNA-derived fragments sdRNA-D19b and -A24 emerged...
7.
Williams J, Houserova D, Johnson B, Dyniewski B, Berroyer A, French H, et al.
Nucleic Acids Res . 2020 May; 48(11):5907-5925. PMID: 32383760
Mammalian antibody switch regions (∼1500 bp) are composed of a series of closely neighboring G4-capable sequences. Whereas numerous structural and genome-wide analyses of roles for minimal G4s in transcriptional regulation...
8.
Barnhill E, Crucello A, Houserova D, King V, Amin S, Roberts J, et al.
RNA Biol . 2019 Aug; 16(11):1643-1657. PMID: 31390935
Noncoding RNA (ncRNA) modulation of gene expression has now been ubiquitously observed across all domains of life. An increasingly apparent role of ncRNAs is to coordinate changes in gene expressions...