Jeffrey Abt
Overview
Explore the profile of Jeffrey Abt including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
2
Citations
28
Followers
0
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Related Specialties
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Recent Articles
1.
Clemens J, Coon T, Busch B, Asgian J, Hudson S, Termin A, et al.
Bioorg Med Chem Lett
. 2014 Jun;
24(15):3398-402.
PMID: 24939756
Extensive phase II metabolism of an advanced PKCε inhibitor resulted in sub-optimal pharmacokinetics in rat marked by elevated clearance. Synthesis of the O-glucuronide metabolite as a standard was followed by...
2.
Zweemer A, Nederpelt I, Vrieling H, Hafith S, Doornbos M, de Vries H, et al.
Mol Pharmacol
. 2013 Jul;
84(4):551-61.
PMID: 23877010
The chemokine receptor CCR2 is a G protein-coupled receptor that is activated primarily by the endogenous CC chemokine ligand 2 (CCL2). Many different small-molecule antagonists have been developed to inhibit...