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Jeffrey A Martinson

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Articles 15
Citations 429
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Recent Articles
1.
El-Far M, Durand M, Turcotte I, Larouche-Anctil E, Sylla M, Zaidan S, et al.
Front Immunol . 2021 May; 12:664371. PMID: 33936102
Despite the success of antiretroviral therapy (ART), people living with HIV (PLWH) are still at higher risk for cardiovascular diseases (CVDs) that are mediated by chronic inflammation. Identification of novel...
2.
Kuniholm M, Xie X, Anastos K, Kaplan R, Xue X, Kovacs A, et al.
J Acquir Immune Defic Syndr . 2014 Oct; 67(3):295-303. PMID: 25314250
Background: Hepatitis C virus (HCV) viremia is thought to have broad systemic effects on the cellular immune system that go beyond its impact on just those T cells that are...
3.
McKinnon L, Hughes S, De Rosa S, Martinson J, Plants J, Brady K, et al.
PLoS One . 2014 Jan; 9(1):e85675. PMID: 24454917
Background: Functional analysis of mononuclear leukocytes in the female genital mucosa is essential for understanding the immunologic effects of HIV vaccines and microbicides at the site of HIV exposure. However,...
4.
Stapleton J, Martinson J, Klinzman D, Xiang J, Desai S, Landay A
AIDS . 2013 Jun; 27(11):1829-32. PMID: 23807277
GB virus C (GBV-C), a pan-lymphotropic flavivirus capable of persistent infection, is associated with prolonged survival and reduced T-cell activation in HIV-infected patients. GBV-C was associated with reduced CD56brt/CD16- natural...
5.
Mondal S, Martinson J, Ghosh S, Watson R, Pahan K
PLoS One . 2013 Jan; 7(12):e51869. PMID: 23284794
In multiple sclerosis (MS) and other autoimmune diseases, the autoreactive T cells overcome the resistance provided by the regulatory T cells (Tregs) due to a decrease in the number of...
6.
Hunt P, Landay A, Sinclair E, Martinson J, Hatano H, Emu B, et al.
PLoS One . 2011 Feb; 6(1):e15924. PMID: 21305005
HIV-infected individuals maintaining undetectable viremia in the absence of therapy (HIV controllers) often maintain high HIV-specific T cell responses, which has spurred the development of vaccines eliciting HIV-specific T cell...
7.
Martinson J, Montoya C, Usuga X, Ronquillo R, Landay A, Desai S
Antimicrob Agents Chemother . 2009 Dec; 54(2):871-81. PMID: 19949061
Plasmacytoid dendritic cells (pDC) contribute to antiviral immunity mainly through recognition of microbial products and viruses via intracellular Toll-like receptor 7 (TLR7) or TLR9, resulting in the production of type...
8.
Zloza A, Schenkel J, Tenorio A, Martinson J, Jeziorczak P, Al-Harthi L
Blood . 2009 Aug; 114(18):3841-53. PMID: 19700667
In humans, approximately 3% of peripheral CD8+ T cells coexpress CD4 dimly on their surface and hence are designated as CD4(dim)CD8(bright) T cells. We evaluated the contribution of this CD4(dim)CD8(bright)...
9.
St John E, Zariffard M, Martinson J, Simoes J, Landay A, Spear G
Virology . 2009 Jan; 385(1):22-7. PMID: 19117586
Women with bacterial vaginosis (BV) have a higher risk of HIV transmission but the cause of risk is unknown. Dendritic cells (DC) are implicated in transmission of HIV and we...
10.
Roy A, Jana A, Yatish K, Freidt M, Fung Y, Martinson J, et al.
Free Radic Biol Med . 2008 Jul; 45(5):686-99. PMID: 18590811
Microglial activation is considered as a hallmark of several neurodegenerative disorders. During microglial activation, the expression of CD11b, the beta-integrin marker of microglia, is increased. However, the molecular mechanism behind...