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Jeffery A Dodge

Explore the profile of Jeffery A Dodge including associated specialties, affiliations and a list of published articles. Areas
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Citations 88
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Recent Articles
1.
Roberts J, San Martin R, Piyarathna D, MacKrell J, Rocha G, Dodge J, et al.
Oncotarget . 2017 Jun; 8(27):44447-44464. PMID: 28591703
Whether vitamin D is chemopreventive and/or has potential therapeutically in prostate cancer is unresolved. One confounding factor is that many prostate cancers express a TMPRSS2:ERG fusion gene whose expression is...
2.
Carson M, Zhang J, Chalmers M, Bocchinfuso W, Holifield K, Masquelin T, et al.
Bioorg Med Chem Lett . 2014 Jun; 24(15):3459-63. PMID: 24974344
Modulation of the vitamin D receptor (VDR) with a ligand has the potential to be useful for the oral treatment of osteoporosis. One component of our lead generation strategy to...
3.
Chalmers M, Pascal B, Willis S, Zhang J, Iturria S, Dodge J, et al.
Int J Mass Spectrom . 2011 Apr; 302(1-3):59-68. PMID: 21528013
Hydrogen/deuterium exchange (HDX) mass spectrometry has been widely applied to the characterization of protein dynamics. More recently, differential HDX has been shown to be effective for the characterization of ligand...
4.
Zhang J, Chalmers M, Stayrook K, Burris L, Garcia-Ordonez R, Pascal B, et al.
Structure . 2010 Oct; 18(10):1332-41. PMID: 20947021
Regulation of nuclear receptor (NR) activity is driven by alterations in the conformational dynamics of the receptor upon ligand binding. Previously, we demonstrated that hydrogen/deuterium exchange (HDX) can be applied...