Jeeyeon Cha
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Explore the profile of Jeeyeon Cha including associated specialties, affiliations and a list of published articles.
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34
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1530
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Recent Articles
1.
Cha J, Tong X, Coate K, Guo M, Liu J, Reynolds G, et al.
J Biol Chem
. 2024 Oct;
300(12):107938.
PMID: 39476962
MAFA and MAFB are related basic-leucine-zipper domain-containing transcription factors which have important overlapping and distinct regulatory roles in a variety of cellular contexts, including hormone production in pancreatic islet cells....
2.
Aguayo-Mazzucato C, Cha J, Thompson P
Front Endocrinol (Lausanne)
. 2024 Jan;
14:1345529.
PMID: 38164496
No abstract available.
3.
Cha J, Aguayo-Mazzucato C, Thompson P
Front Endocrinol (Lausanne)
. 2023 Sep;
14:1212716.
PMID: 37720527
Cellular senescence is a response to a wide variety of stressors, including DNA damage, oncogene activation and physiologic aging, and pathologically accelerated senescence contributes to human disease, including diabetes mellitus....
4.
Cha J, Tong X, Coate K, Guo M, Liu J, Reynolds G, et al.
bioRxiv
. 2023 Sep;
PMID: 37662349
MAFA and MAFB are related basic-leucine-zipper domain containing transcription factors which have important overlapping and distinct regulatory roles in a variety of cellular contexts, including hormone production in pancreatic islet...
5.
Cha J, Tong X, Walker E, Dahan T, Cochrane V, Ashe S, et al.
JCI Insight
. 2023 Aug;
8(16).
PMID: 37606041
Type 2 diabetes (T2D) is associated with compromised identity of insulin-producing pancreatic islet β cells, characterized by inappropriate production of other islet cell-enriched hormones. Here, we examined how hormone misexpression...
6.
Walker E, Cha J, Tong X, Guo M, Liu J, Yu S, et al.
Cell Rep
. 2021 Oct;
37(2):109813.
PMID: 34644565
A heterozygous missense mutation of the islet β cell-enriched MAFA transcription factor (p.Ser64Phe [S64F]) is found in patients with adult-onset β cell dysfunction (diabetes or insulinomatosis), with men more prone...
7.
Coate K, Cha J, Shrestha S, Wang W, Mateus Goncalves L, Almaca J, et al.
Cell Metab
. 2020 Nov;
32(6):1028-1040.e4.
PMID: 33207245
Isolated reports of new-onset diabetes in individuals with COVID-19 have led to the hypothesis that SARS-CoV-2 is directly cytotoxic to pancreatic islet β cells. This would require binding and entry...
8.
Coate K, Cha J, Shrestha S, Wang W, Mateus Goncalves L, Almaca J, et al.
bioRxiv
. 2020 Oct;
PMID: 33106804
Reports of new-onset diabetes and diabetic ketoacidosis in individuals with COVID-19 have led to the hypothesis that SARS-CoV-2, the virus that causes COVID-19, is directly cytotoxic to pancreatic islet β...
9.
Actkins K, Singh K, Hucks D, Velez Edwards D, Aldrich M, Cha J, et al.
J Clin Endocrinol Metab
. 2020 Sep;
106(1):153-167.
PMID: 32961557
Context: Polycystic ovary syndrome (PCOS) is one of the leading causes of infertility, yet current diagnostic criteria are ineffective at identifying patients whose symptoms reside outside strict diagnostic criteria. As...
10.
Li X, Itani O, Haataja L, Dumas K, Yang J, Cha J, et al.
Sci Adv
. 2019 Dec;
5(12):eaax0292.
PMID: 31840061
The mechanistic basis for the biogenesis of peptide hormones and growth factors is poorly understood. Here, we show that the conserved endoplasmic reticulum membrane translocon-associated protein α (TRAPα), also known...