Jedd Hillegass
Overview
Explore the profile of Jedd Hillegass including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
174
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0
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Recent Articles
11.
Gould J, Carvajal I, Davidson T, Graham J, Hillegass J, Julien S, et al.
Regul Toxicol Pharmacol
. 2018 Oct;
100:35-44.
PMID: 30291877
Protein therapeutics represent a rapidly growing proportion of new medicines being developed by the pharmaceutical industry. As with any new drug, an Occupational Exposure Limit (OEL) should be developed to...
12.
Myatt G, Ahlberg E, Akahori Y, Allen D, Amberg A, Anger L, et al.
Regul Toxicol Pharmacol
. 2018 Apr;
96:1-17.
PMID: 29678766
The present publication surveys several applications of in silico (i.e., computational) toxicology approaches across different industries and institutions. It highlights the need to develop standardized protocols when conducting toxicity-related predictions....
13.
Chilton M, Macmillan D, Steger-Hartmann T, Hillegass J, Bellion P, Vuorinen A, et al.
Regul Toxicol Pharmacol
. 2018 Mar;
95:227-235.
PMID: 29580972
A previously published fragmentation method for making reliable negative in silico predictions has been applied to the problem of predicting skin sensitisation in humans, making use of a dataset of...
14.
Canipa S, Chilton M, Hemingway R, Macmillan D, Myden A, Plante J, et al.
J Appl Toxicol
. 2017 Mar;
37(8):985-995.
PMID: 28244128
Dermal contact with chemicals may lead to an inflammatory reaction known as allergic contact dermatitis. Consequently, it is important to assess new and existing chemicals for their skin sensitizing potential...
15.
Shukla A, Miller J, Cason C, Sayan M, MacPherson M, Beuschel S, et al.
Clin Cancer Res
. 2013 Mar;
19(8):2071-83.
PMID: 23446998
Purpose: Malignant mesothelioma is a devastating disease with a need for new treatment strategies. In the present study, we showed the importance of extracellular signal-regulated kinase 5 (ERK5) in malignant...
16.
Shukla A, MacPherson M, Hillegass J, Ramos-Nino M, Alexeeva V, Vacek P, et al.
Am J Respir Cell Mol Biol
. 2008 Dec;
41(1):114-23.
PMID: 19097984
Human mesothelial cells (LP9/TERT-1) were exposed to low and high (15 and 75 microm(2)/cm(2) dish) equal surface area concentrations of crocidolite asbestos, nonfibrous talc, fine titanium dioxide (TiO2), or glass...