Jeannie Chin
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Explore the profile of Jeannie Chin including associated specialties, affiliations and a list of published articles.
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43
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3097
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Recent Articles
1.
Blanco F, Saifullah M, Cheng J, Abella C, Scala F, Firozi K, et al.
J Neurosci
. 2024 Dec;
45(6).
PMID: 39725519
Excitatory synapses and the actin-rich dendritic spines on which they reside are indispensable for information processing and storage in the brain. In the adult hippocampus, excitatory synapses must balance plasticity...
2.
Leeman-Markowski B, Chin J, Leitner D, Vossel K
Front Neurol
. 2024 Aug;
15:1441996.
PMID: 39193148
No abstract available.
3.
Sun X, Badachhape A, Bhandari P, Chin J, Annapragada A, Tanifum E
Front Neurosci
. 2024 Aug;
18:1428736.
PMID: 39114484
The pathogenesis of Parkinson's disease (PD) is characterized by progressive deposition of alpha-synuclein (α-syn) aggregates in dopaminergic neurons and neuroinflammation. Noninvasive imaging of α-syn aggregate accumulation and neuroinflammation can elicit...
4.
Stephens G, Park J, Eagle A, You J, Silva-Perez M, Fu C, et al.
Prog Neurobiol
. 2024 Apr;
237:102612.
PMID: 38642602
Recurrent seizures lead to accumulation of the activity-dependent transcription factor ∆FosB in hippocampal dentate granule cells in both mouse models of epilepsy and mouse models of Alzheimer's disease (AD), which...
5.
Clasadonte J, Deprez T, Stephens G, Mairet-Coello G, Cortin P, Boutier M, et al.
Front Mol Neurosci
. 2024 Jan;
16:1324922.
PMID: 38283700
Activity induced transcription factor ΔFosB plays a key role in different CNS disorders including epilepsy, Alzheimer's disease, and addiction. Recent findings suggest that ΔFosB drives cognitive deficits in epilepsy and...
6.
Fu C, You J, Mohila C, Rissman R, Yoshor D, Viaene A, et al.
Front Neurol
. 2024 Jan;
14:1331194.
PMID: 38274865
Epilepsy is a chronic neurological disorder characterized by recurrent seizures, and is often comorbid with other neurological and neurodegenerative diseases, such as Alzheimer's disease (AD). Patients with recurrent seizures often...
7.
Shrestha J, Santerre M, Allen C, Arjona S, Merali C, Mukerjee R, et al.
Front Aging Neurosci
. 2022 May;
14:811481.
PMID: 35615594
HIV-associated neurocognitive disorders (HAND) remain an unsolved problem that persists despite using antiretroviral therapy. We have obtained data showing that HIV-gp120 protein contributes to neurodegeneration through metabolic reprogramming. This led...
8.
Jagirdar R, Fu C, Park J, Corbett B, Seibt F, Beierlein M, et al.
Sci Transl Med
. 2021 Nov;
13(618):eabh4284.
PMID: 34731016
Sleep disruptions promote increases of amyloid β (Aβ) and tau in the brain and increase Alzheimer’s disease (AD) risk, but the precise mechanisms that give rise to sleep disturbances have...
9.
Stephens G, Fu C, Romain C, Zheng Y, Botterill J, Scharfman H, et al.
Front Neurosci
. 2020 Jun;
14:472.
PMID: 32536852
Seizure incidence is increased in Alzheimer's disease (AD) patients and mouse models, and treatment with the antiseizure drug levetiracetam improves cognition. We reported that one mechanism by which seizures can...
10.
OMalley J, Seibt F, Chin J, Beierlein M
J Neurosci
. 2020 May;
40(25):4813-4823.
PMID: 32414784
During sleep, neurons in the thalamic reticular nucleus (TRN) participate in distinct types of oscillatory activity. While the reciprocal synaptic circuits between TRN and sensory relay nuclei are known to...