Jeannette N Williams
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Explore the profile of Jeannette N Williams including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
173
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Recent Articles
1.
Williams J, Weynants V, Poolman J, Heckels J, Christodoulides M
Vaccine
. 2014 Feb;
32(11):1280-6.
PMID: 24486354
Human volunteers were vaccinated with experimental Neisseria meningitidis serogroup B vaccines based on strain H44/76 detoxified L3 lipooligosaccharide (LOS)-derived outer membrane vesicles (OMV) or the licensed Cuban vaccine, VA-MENGOC-BC. Some...
2.
Phillips R, Williams J, Tan W, Bielecka M, Thompson H, Hung M, et al.
Vaccine
. 2013 Apr;
31(22):2584-90.
PMID: 23566947
Sera from individuals colonized with Neisseria meningitidis and from patients with meningococcal disease contain antibodies specific for the neisserial heat-shock/chaperonin (Chp)60 protein. In this study, immunization of mice with recombinant...
3.
Williams J, Christodoulides M, Heckels J
Methods Mol Biol
. 2011 Oct;
799:343-60.
PMID: 21993655
The availability of Neisseria genome sequences together with improvements in proteomic technologies provide the opportunity to study at high resolution the immune response to Neisseria meningitidis. In this chapter, we...
4.
Hung M, Salim O, Williams J, Heckels J, Christodoulides M
Infect Immun
. 2011 Jun;
79(9):3784-91.
PMID: 21708989
A gene encoding a 29-kDa protein from Neisseria meningitidis serogroup B strain MC58 with homology to the macrophage infectivity potentiator (MIP) protein of Legionella pneumophila was cloned and expressed in...
5.
Heckels J, Williams J
Genome Med
. 2010 Jul;
2(7):43.
PMID: 20670394
There is a particular need for an effective vaccine against life-threatening meningitis and septicemia caused by Neisseria meningitidis (meningococcus) serogroup B strains. Vaccine strategies incorporating capsular polysaccharide have proved effective...
6.
Williams J, Skipp P, OConnor C, Christodoulides M, Heckels J
Infect Immun
. 2009 Sep;
77(11):5080-9.
PMID: 19737898
The potential protective effect of existing vaccines against serogroup B meningococci, based on outer membrane proteins, is limited by strain restriction and apparent short duration of immune responses. In contrast,...
7.
Kumar P, Williams J, Durkin K, Heckels J, Friedmann P, Healy E, et al.
Inflamm Res
. 2009 Aug;
59(2):105-13.
PMID: 19685205
Objective And Design: alpha-Melanoycte stimulating hormone (alpha-MSH), a neuropeptide hormone with reported anti-microbial and immuno-modulatory properties in vitro, has previously been detected in the cerebrospinal fluid of children with bacterial...
8.
Zhu D, Williams J, Rice J, Stevenson F, Heckels J, Christodoulides M
Infect Immun
. 2007 Oct;
76(1):334-8.
PMID: 17967859
An experimental DNA plasmid vaccine was developed based on a well-characterized and protective peptide epitope derived from a bacterial porin protein. For this study, we used the P1.16b serosubtype epitope,...
9.
Williams J, Skipp P, Humphries H, Christodoulides M, OConnor C, Heckels J
Infect Immun
. 2006 Dec;
75(3):1364-72.
PMID: 17158897
Current experimental vaccines against serogroup B Neisseria meningitidis are based on meningococcal outer membrane (OM) proteins present in outer membrane vesicles (OMV) in which toxic lipopolysaccharide is depleted by detergent...
10.
Humphries H, Williams J, Blackstone R, Jolley K, Yuen H, Christodoulides M, et al.
Vaccine
. 2005 Aug;
24(1):36-44.
PMID: 16105711
Four serosubtypes (P1.7, 16, P1.7-2, 4, P1.19, 15 and P1.5-1, 10-4) of the PorA outer-membrane protein of Neisseria meningitidis were purified as recombinant proteins and incorporated into liposomes to investigate...