Jeanne M Frederick
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Explore the profile of Jeanne M Frederick including associated specialties, affiliations and a list of published articles.
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53
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2329
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Recent Articles
1.
Li B, George E, Vachali P, Chang F, Gorusupudi A, Arunkumar R, et al.
Exp Eye Res
. 2023 Mar;
229:109429.
PMID: 36863431
The macular carotenoids lutein and zeaxanthin are taken up from the bloodstream into the human retina through a selective process, for which the HDL cholesterol receptor scavenger receptor BI (SR-BI)...
2.
Gerstner C, Reed M, Dahl T, Ying G, Frederick J, Baehr W
Cells
. 2023 Jan;
12(1).
PMID: 36611941
Arf-like protein 2 (ARL2) is a ubiquitously expressed small GTPase with multiple functions. In a cell culture, ARL2 participates with tubulin cofactor D (TBCD) in the neogenesis of tubulin αβ-heterodimers,...
3.
Reed M, Takemaru K, Ying G, Frederick J, Baehr W
PLoS Genet
. 2022 Sep;
18(9):e1010154.
PMID: 36074756
Centrosomal protein of 164 kDa (CEP164) is located at distal appendages of primary cilia and is necessary for basal body (BB) docking to the apical membrane. To investigate the function...
4.
Li B, Vachali P, Chang F, Gorusupudi A, Arunkumar R, Shi L, et al.
Arch Biochem Biophys
. 2021 Dec;
716:109111.
PMID: 34942193
Supplementation with antioxidant carotenoids is a therapeutic strategy to protect against age-related macular degeneration (AMD); however, the transport mechanism of carotenoids from the liver to the retina is still not...
5.
Sharif A, Gerstner C, Cady M, Arshavsky V, Mitchell C, Ying G, et al.
J Biol Chem
. 2021 Mar;
296:100529.
PMID: 33711342
INPP5E, also known as pharbin, is a ubiquitously expressed phosphatidylinositol polyphosphate 5-phosphatase that is typically located in the primary cilia and modulates the phosphoinositide composition of membranes. Mutations to or...
6.
Li B, George E, Rognon G, Gorusupudi A, Ranganathan A, Chang F, et al.
Proc Natl Acad Sci U S A
. 2020 May;
117(22):12352-12358.
PMID: 32409609
Lutein and zeaxanthin are xanthophyll carotenoids that are highly concentrated in the human macula, where they protect the eye from oxidative damage and improve visual performance. Distinguishing lutein from zeaxanthin...
7.
Frederick J, Hanke-Gogokhia C, Ying G, Baehr W
Biol Chem
. 2019 Dec;
401(5):573-584.
PMID: 31811799
Photoreceptors are polarized neurons, with specific subcellular compartmentalization and unique requirements for protein expression and trafficking. Each photoreceptor contains an outer segment (OS) where vision begins, an inner segment (IS)...
8.
Hanke-Gogokhia C, Chiodo V, Hauswirth W, Frederick J, Baehr W
Mol Vis
. 2019 Feb;
24:834-846.
PMID: 30713422
Purpose: Recessive mutations in the human gene are associated with Senior-Løken syndrome (SLS), a ciliopathy presenting with nephronophthisis and Leber congenital amaurosis (LCA). -knockout mice develop LCA without nephronophthisis. Mutant...
9.
Ying G, Frederick J, Baehr W
J Biol Chem
. 2019 Jan;
294(11):3957-3973.
PMID: 30647131
Centrins (CETN1-4) are ubiquitous and conserved EF-hand-family Ca-binding proteins associated with the centrosome, basal body, and transition zone. Deletion of CETN1 or CETN2 in mice causes male infertility or dysosmia,...
10.
Baehr W, Hanke-Gogokhia C, Sharif A, Reed M, Dahl T, Frederick J, et al.
Prog Retin Eye Res
. 2018 Dec;
71:26-56.
PMID: 30590118
Photoreceptors are polarized neurons, with very specific subcellular compartmentalization and unique requirements for protein expression and trafficking. Each photoreceptor contains an outer segment, the site of photon capture that initiates...