Jean Paul Ten Klooster
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Explore the profile of Jean Paul Ten Klooster including associated specialties, affiliations and a list of published articles.
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18
Citations
781
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Recent Articles
1.
Oost M, Ijaz A, van Haarlem D, van Summeren K, Velkers F, Kraneveld A, et al.
Sci Rep
. 2022 Jun;
12(1):10563.
PMID: 35732901
Intestinal organoids are advanced cellular models, which are widely used in mammalian studies to mimic and study in vivo intestinal function and host-pathogen interactions. Growth factors WNT3 and RSPO1 are...
2.
Aarts J, Boleij A, Pieters B, Feitsma A, van Neerven R, Ten Klooster J, et al.
Front Immunol
. 2021 Aug;
12:703277.
PMID: 34394100
Review Criteria: The search terms "extracellular vesicles", "exosomes", "microvesicles", "rheumatoid arthritis", "gut-joint axis", "milk", and "experimental arthritis" were used. English-language full text papers (published between 1980 and 2021) were identified...
3.
Ten Klooster J, Bol-Schoenmakers M, van Summeren K, van Vliet A, de Haan C, van Kuppeveld F, et al.
Commun Biol
. 2021 May;
4(1):631.
PMID: 34045640
IL22 is an important cytokine involved in the intestinal defense mechanisms against microbiome. By using ileum-derived organoids, we show that the expression of anti-microbial peptides (AMPs) and anti-viral peptides (AVPs)...
4.
Biel C, Bigaeva E, Hesse M, Bomers J, van Summeren K, Teunis M, et al.
Toxicol In Vitro
. 2020 Aug;
69:104974.
PMID: 32828807
Precision-cut intestinal slices (PCIS) are used to study intestinal (patho)physiology, drug efficacy, toxicity, transport and metabolism ex vivo. One of the factors that limit the use of PCIS is a...
5.
Ten Klooster J, Sotiriou A, Boeren S, Vaessen S, Vervoort J, Pieters R
Arch Biochem Biophys
. 2018 Mar;
644:81-92.
PMID: 29526533
Currently, there is a worldwide increase of patients with type 2 diabetes (T2D). During the progression of healthy obese to T2D status, there is an influx of immune cells, in...
6.
Wang Y, Plastina P, Vincken J, Jansen R, Balvers M, Ten Klooster J, et al.
ACS Chem Neurosci
. 2017 Mar;
8(3):548-557.
PMID: 28292183
Several studies indicate that the n-3 long-chain polyunsaturated fatty acid docosahexaenoic acid (DHA) contributes to an attenuated inflammatory status in the development of neurodegenerative disorders, such as Alzheimer's and Parkinson's...
7.
van der Wielen N, Ten Klooster J, Muckenschnabl S, Pieters R, Hendriks H, Witkamp R, et al.
J Nutr
. 2016 Nov;
146(12):2429-2435.
PMID: 27798332
Background: Glucagon-like peptide 1 (GLP-1) contributes to satiety and plays a pivotal role in insulin secretion and glucose homeostasis. Similar to GLP-1, peptide YY (PYY) and cholecystokinin also influence food...
8.
Poland M, Ten Klooster J, Wang Z, Pieters R, Boekschoten M, Witkamp R, et al.
Biochim Biophys Acta
. 2016 Sep;
1861(12 Pt A):2020-2028.
PMID: 27663185
Conjugates of fatty acids and amines, including endocannabinoids, are known to play important roles as endogenous signaling molecules. Among these, the ethanolamine conjugate of the n-3 poly unsaturated long chain...
9.
Gloerich M, Ten Klooster J, Vliem M, Koorman T, Zwartkruis F, Clevers H, et al.
Nat Cell Biol
. 2012 Jul;
14(8):793-801.
PMID: 22797597
The microvillus brush border at the apex of the highly polarized enterocyte allows the regulated uptake of nutrients from the intestinal lumen. Here, we identify the small G protein Rap2A...
10.
Jansen M, Ten Klooster J, Offerhaus G, Clevers H
Physiol Rev
. 2009 Jul;
89(3):777-98.
PMID: 19584313
Research on the LKB1 tumor suppressor protein mutated in cancer-prone Peutz-Jeghers patients has continued at a feverish pace following exciting developments linking energy metabolism and cancer development. This review summarizes...