Jean Marc Egly
Overview
Explore the profile of Jean Marc Egly including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
792
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Costanzo F, Paccosi E, Proietti-De-Santis L, Egly J
Trends Cell Biol
. 2024 Jun;
34(10):882-895.
PMID: 38910038
To face genotoxic stress, eukaryotic cells evolved extremely refined mechanisms. Defects in counteracting the threat imposed by DNA damage underlie the rare disease Cockayne syndrome (CS), which arises from mutations...
2.
Costanzo F, Martinez Diez M, Santamaria Nunez G, Diaz-Hernandez J, Genes Robles C, Diez Perez J, et al.
EMBO Mol Med
. 2022 Mar;
14(4):e14841.
PMID: 35263037
Small-Cell Lung Cancer (SCLC) is an aggressive neuroendocrine malignancy with a poor prognosis. Here, we focus on the neuroendocrine SCLC subtypes, SCLC-A and SCLC-N, whose transcription addiction was driven by...
3.
Kim J, Saint-Andre C, Lim H, Hwang C, Egly J, Cho Y
J Biol Chem
. 2015 Feb;
290(13):8321-30.
PMID: 25681444
The Ssl1/p44 subunit is a core component of the yeast/mammalian general transcription factor TFIIH, which is involved in transcription and DNA repair. Ssl1/p44 binds to and stimulates the Rad3/XPD helicase...
4.
Orioli D, Compe E, Nardo T, Mura M, Giraudon C, Botta E, et al.
Hum Mol Genet
. 2012 Dec;
22(6):1061-73.
PMID: 23221806
Mutations in the XPD subunit of the transcription/DNA repair factor (TFIIH) give rise to trichothiodystrophy (TTD), a rare hereditary multisystem disorder with skin abnormalities. Here, we show that TTD primary...
5.
Bueren-Calabuig J, Giraudon C, Galmarini C, Egly J, Gago F
Nucleic Acids Res
. 2011 Jul;
39(18):8248-57.
PMID: 21727089
The difference in melting temperature of a double-stranded (ds) DNA molecule in the absence and presence of bound ligands can provide experimental information about the stabilization brought about by ligand...
6.
Le May N, Mota-Fernandes D, Velez-Cruz R, Iltis I, Biard D, Egly J
Mol Cell
. 2010 Apr;
38(1):54-66.
PMID: 20385089
Upon gene activation, we found that RNA polymerase II transcription machinery assembles sequentially with the nucleotide excision repair (NER) factors at the promoter. This recruitment occurs in absence of exogenous...
7.
Hashimoto S, Egly J
Hum Mol Genet
. 2009 Oct;
18(R2):R224-30.
PMID: 19808800
Trichothiodystrophy (TTD) is a rare autosomal recessive disorder characterized by brittle hair and also associated with various systemic symptoms. Approximately half of TTD patients exhibit photosensitivity, resulting from the defect...
8.
Aguilar-Fuentes J, Fregoso M, Herrera M, Reynaud E, Braun C, Egly J, et al.
PLoS Genet
. 2008 Nov;
4(11):e1000253.
PMID: 19008953
Mutations in certain subunits of the DNA repair/transcription factor complex TFIIH are linked to the human syndromes xeroderma pigmentosum (XP), Cockayne's syndrome (CS), and trichothiodystrophy (TTD). One of these subunits,...
9.
Bernardes de Jesus B, Bjoras M, Coin F, Egly J
Mol Cell Biol
. 2008 Sep;
28(23):7225-35.
PMID: 18809580
XPC is responsible for DNA damage sensing in nucleotide excision repair (NER). Mutations in XPC lead to a defect in NER and to xeroderma pigmentosum (XP-C). Here, we analyzed the...
10.
Coin F, Oksenych V, Mocquet V, Groh S, Blattner C, Egly J
Mol Cell
. 2008 Jul;
31(1):9-20.
PMID: 18614043
The transcription/DNA repair factor TFIIH is organized into a core that associates with the CDK-activating kinase (CAK) complex. Using chromatin immunoprecipitation, we have followed the composition of TFIIH over time...