Jean L J M Scheijen
Overview
Explore the profile of Jean L J M Scheijen including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
893
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Recent Articles
1.
Vangrieken P, Scheijen J, Schiffers P, van de Waarenburg M, Foulquier S, Schalkwijk C
Sci Rep
. 2025 Feb;
15(1):6025.
PMID: 39972072
Methylglyoxal (MGO), a glycolysis by-product and precursor to advanced glycation endproducts (AGEs), is associated with glucose intolerance, type 2 diabetes, and vascular dysfunction. This study examined the long-term effects of...
2.
Koene E, Buziau A, Cassiman D, Cox T, Bons J, Scheijen J, et al.
J Clin Invest
. 2025 Feb;
PMID: 39932807
No abstract available.
3.
Zhang X, van Greevenbroek M, Scheijen J, Eussen S, Kelly J, Stehouwer C, et al.
J Endocrinol Invest
. 2025 Jan;
PMID: 39847265
Purpose: Elevated methylglyoxal (MGO) levels and altered immune cell responses are observed in diabetes. MGO is thought to modulate immune cell activation. The current study investigated whether fasting or post-glucose-load...
4.
Berends E, Vangrieken P, Amiri N, van de Waarenburg M, Scheijen J, Hermes D, et al.
Mol Neurobiol
. 2024 Oct;
62(4):4190-4202.
PMID: 39414727
Diabetes and other age-related diseases are associated with an increased risk of cognitive impairment, but the underlying mechanisms remain poorly understood. Methylglyoxal (MGO), a by-product of glycolysis and a major...
5.
Berends E, Pencheva M, van de Waarenburg M, Scheijen J, Hermes D, Wouters K, et al.
J Physiol
. 2024 Sep;
602(22):6209-6223.
PMID: 39316027
Diabetes is associated with cognitive impairment, but the underlying mechanism remains unclear. Methylglyoxal (MGO), a precursor to advanced glycation endproducts (AGEs), is elevated in diabetes and linked to microvascular dysfunction....
6.
Sun D, van Greevenbroek M, Scheijen J, Kelly J, Schalkwijk C, Wouters K
J Clin Endocrinol Metab
. 2024 Sep;
PMID: 39315630
Context: Glucose excursions in persons with diabetes may drive chronic inflammation. Methylglyoxal (MGO) is formed from glucose, is elevated in persons with diabetes, and is a potent glycating agent linked...
7.
Vangrieken P, Al-Nasiry S, Remels A, Schiffers P, Janssen E, Nass S, et al.
Hypertension
. 2024 May;
81(7):1537-1549.
PMID: 38752345
Background: Preeclampsia is a multifaceted syndrome that includes maternal vascular dysfunction. We hypothesize that increased placental glycolysis and hypoxia in preeclampsia lead to increased levels of methylglyoxal (MGO), consequently causing...
8.
Bednarska K, Fecka I, Scheijen J, Ahles S, Vangrieken P, Schalkwijk C
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685975
Reactive α-dicarbonyls (α-DCs), such as methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG), are potent precursors in the formation of advanced glycation end products (AGEs). In particular, MGO and MGO-derived AGEs...
9.
Buziau A, Scheijen J, Stehouwer C, Schalkwijk C, Brouwers M
Metabol Open
. 2023 May;
18:100245.
PMID: 37251289
Background And Objective: Previous experimental studies have shown that fructose interacts with glucose metabolism by increasing hepatic glucose uptake. However, human studies investigating the effects of small ('catalytic') amounts of...
10.
Buziau A, Blokland G, Schalkwijk C, Scheijen J, Simons P, Eussen S, et al.
Diabetes Care
. 2023 Mar;
46(4):e97-e98.
PMID: 36952606
No abstract available.