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Jean E Schwarzbauer

Explore the profile of Jean E Schwarzbauer including associated specialties, affiliations and a list of published articles. Areas
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Articles 86
Citations 2991
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Recent Articles
21.
Raitman I, Huang M, Williams S, Friedman B, Godula K, Schwarzbauer J
Matrix Biol . 2017 Dec; 67:107-122. PMID: 29223498
During extracellular matrix (ECM) assembly, fibronectin (FN) fibrils are irreversibly converted into a detergent-insoluble form which, through FN's multi-domain structure, can interact with collagens, matricellular proteins, and growth factors to...
22.
Goyal R, Vega M, Pastino A, Singh S, Guvendiren M, Kohn J, et al.
J Biomed Mater Res A . 2017 Apr; 105(8):2162-2170. PMID: 28371271
A major challenge of tissue engineering is to generate materials that combine bioactivity with stability in a form that captures the robust nature of native tissues. Here we describe a...
23.
Miller C, Budoff G, Prenner J, Schwarzbauer J
Exp Biol Med (Maywood) . 2016 Nov; 242(1):1-7. PMID: 27798121
Retinal fibrosis, characterized by dysregulation of extracellular matrix (ECM) protein deposition by retinal endothelial cells, pigment epithelial cells, and other resident cell-types, is a unifying feature of several common retinal...
24.
Harris G, Madigan N, Lancaster K, Enquist L, Windebank A, Schwartz J, et al.
Matrix Biol . 2016 Sep; 60-61:176-189. PMID: 27641621
Spinal cord and peripheral nerve injuries require the regeneration of nerve fibers across the lesion site for successful recovery. Providing guidance cues and soluble factors to promote neurite outgrowth and...
25.
Schwarzbauer J, Leader W, Drubin D
Mol Biol Cell . 2016 Sep; 27(18):2803. PMID: 27634742
No abstract available.
26.
Pastino A, Greco T, Mathias R, Cristea I, Schwarzbauer J
Matrix Biol . 2016 Jul; 59:39-53. PMID: 27425255
Advanced glycation endproducts (AGEs) are a heterogeneous group of compounds that form via non-enzymatic glycation of proteins throughout our lifespan and at a higher rate in certain chronic diseases such...
27.
Vega M, Schwarzbauer J
Curr Opin Cell Biol . 2016 Apr; 42:1-6. PMID: 27062478
Tissue formation and cell differentiation depend on a properly assembled extracellular matrix (ECM). Fibronectin is a key constituent of the pericellular ECM, forming essential connections between cell surface integrin receptors...
28.
Meighan C, Schwarzbauer J
Int J Dev Biol . 2014 Oct; 58(5):325-33. PMID: 25354452
Integrin signaling impacts many developmental processes. The complexity of these signals increases when multiple, unique integrin heterodimers are expressed during a single developmental event. Since integrin heterodimers have different signaling...
29.
Singh P, Schwarzbauer J
J Cell Sci . 2014 Aug; 127(Pt 20):4420-8. PMID: 25146392
Mesenchymal cell condensation is the initiating event in endochondral bone formation. Cell condensation is followed by differentiation into chondrocytes, which is accompanied by induction of chondrogenic gene expression. Gene mutations...
30.
Miller C, Pozzi A, Zent R, Schwarzbauer J
Mol Biol Cell . 2014 Jun; 25(16):2342-50. PMID: 24943838
The filtration unit of the kidney is the glomerulus, a capillary network supported by mesangial cells and extracellular matrix (ECM). Glomerular function is compromised in diabetic nephropathy (DN) by uncontrolled...