Jean E Schwarzbauer
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Explore the profile of Jean E Schwarzbauer including associated specialties, affiliations and a list of published articles.
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86
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2991
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Recent Articles
11.
Siddiqui A, Brunner R, Harris G, Miller 2nd A, Waletzki B, Schmeichel A, et al.
Biomedicines
. 2021 Apr;
9(5).
PMID: 33925613
Spinal cord injury (SCI) results in cell death, demyelination, and axonal loss. The spinal cord has a limited ability to regenerate, and current clinical therapies for SCI are not effective...
12.
Garrison C, Schwarzbauer J
Mol Biol Cell
. 2021 Feb;
32(8):739-752.
PMID: 33625865
The physical structure of the extracellular matrix (ECM) is tissue-specific and fundamental to normal tissue function. Proper alignment of ECM fibers is essential for the functioning of a variety of...
13.
Vega M, Finlay J, Vasishtha M, Schwarzbauer J
Matrix Biol Plus
. 2021 Feb;
8:100048.
PMID: 33543041
Mesangial cells are the major extracellular matrix (ECM)-producing cells in the kidney glomerulus and, when exposed to elevated glucose levels, they up-regulate assembly of fibronectin (FN) and other ECM proteins....
14.
Bandini S, Spechler J, Donnelly P, Lim K, Arnold C, Schwarzbauer J, et al.
ACS Biomater Sci Eng
. 2021 Jan;
3(12):3123-3127.
PMID: 33445355
Polymeric sheets were perforated by laser ablation and were uncompromised by a debris field when first treated with a thin layer of photoresist. Polymer sheets perforated with holes comprising 5,...
15.
Garrison C, Singh-Varma A, Pastino A, Steele J, Kohn J, Murthy N, et al.
J Biomed Mater Res A
. 2020 Jul;
109(5):733-744.
PMID: 32654327
Tissue regeneration often requires recruitment of different cell types and rebuilding of two or more tissue layers to restore function. Here, we describe the creation of a novel multilayered scaffold...
16.
Vega M, Kastberger B, Wehrle-Haller B, Schwarzbauer J
Cells
. 2020 Mar;
9(3).
PMID: 32182705
Diabetic nephropathy, a devastating consequence of diabetes mellitus, is characterized by the accumulation of extracellular matrix (ECM) that disrupts the kidney's filtration apparatus. Elevated glucose levels increase the deposition of...
17.
Saunders J, Schwarzbauer J
Mol Biol Cell
. 2019 Jun;
30(17):2218-2226.
PMID: 31242089
The extracellular matrix (ECM) proteins fibronectin (FN) and type I collagen (collagen I) are codistributed in many tissues, and collagens have been shown to depend on an FN matrix for...
18.
Chen J, Lim K, Bandini S, Harris G, Spechler J, Arnold C, et al.
ACS Appl Mater Interfaces
. 2019 Mar;
11(17):15411-15416.
PMID: 30924633
A two-step synthesis is described for activating the surface of a fully hydrated hydrogel that is of interest as a possible scaffold for neural regeneration devices. The first step exploits...
19.
Hsia H, Weaver M, Schwarzbauer J
Ann Plast Surg
. 2018 Jun;
81(6S Suppl 1):S89-S96.
PMID: 29851721
Background: Despite the widespread practice of using biologic scaffolds for soft tissue reinforcement over prosthetic implants, the impact of acellular dermal matrix (ADM) on surgical wound fluid biomarkers over the...
20.
Harris G, Raitman I, Schwarzbauer J
Methods Cell Biol
. 2018 Jan;
143:97-114.
PMID: 29310794
The ability to create cell-derived decellularized matrices in a dish gives researchers the opportunity to possess a bioactive, biocompatible material made up of fibrillar proteins and other factors that recapitulates...