Jean C Zenklusen
Overview
Explore the profile of Jean C Zenklusen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
3104
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ellrott K, Wong C, Yau C, Castro M, Lee J, Karlberg B, et al.
Cancer Cell
. 2025 Jan;
43(2):195-212.e11.
PMID: 39753139
Molecular subtypes, such as defined by The Cancer Genome Atlas (TCGA), delineate a cancer's underlying biology, bringing hope to inform a patient's prognosis and treatment plan. However, most approaches used...
2.
Sundaram L, Kumar A, Zatzman M, Salcedo A, Ravindra N, Shams S, et al.
Science
. 2024 Sep;
385(6713):eadk9217.
PMID: 39236169
To identify cancer-associated gene regulatory changes, we generated single-cell chromatin accessibility landscapes across eight tumor types as part of The Cancer Genome Atlas. Tumor chromatin accessibility is strongly influenced by...
3.
Thomas N, Dreval K, Gerhard D, Hilton L, Abramson J, Ambinder R, et al.
Blood
. 2022 Oct;
141(8):904-916.
PMID: 36201743
Burkitt lymphoma (BL) accounts for most pediatric non-Hodgkin lymphomas, being less common but significantly more lethal when diagnosed in adults. Much of the knowledge of the genetics of BL thus...
4.
Chambwe N, Sayaman R, Hu D, Huntsman S, Kemal A, Caesar-Johnson S, et al.
STAR Protoc
. 2022 Aug;
3(3):101586.
PMID: 35942349
Differential mRNA expression between ancestry groups can be explained by both genetic and environmental factors. We outline a computational workflow to determine the extent to which germline genetic variation explains...
5.
Robertson A, Yau C, Carrot-Zhang J, Damrauer J, Knijnenburg T, Chambwe N, et al.
STAR Protoc
. 2021 May;
2(2):100483.
PMID: 33982016
Cellular and molecular aberrations contribute to the disparity of human cancer incidence and etiology between ancestry groups. Multiomics profiling in The Cancer Genome Atlas (TCGA) allows for querying of the...
6.
Carrot-Zhang J, Chambwe N, Damrauer J, Knijnenburg T, Robertson A, Yau C, et al.
Cancer Cell
. 2020 May;
37(5):639-654.e6.
PMID: 32396860
We evaluated ancestry effects on mutation rates, DNA methylation, and mRNA and miRNA expression among 10,678 patients across 33 cancer types from The Cancer Genome Atlas. We demonstrated that cancer...
7.
Gao G, Parker J, Reynolds S, C Silva T, Wang L, Zhou W, et al.
Cell Syst
. 2019 Jul;
9(1):24-34.e10.
PMID: 31344359
We present a systematic analysis of the effects of synchronizing a large-scale, deeply characterized, multi-omic dataset to the current human reference genome, using updated software, pipelines, and annotations. For each...
8.
Corces M, Granja J, Shams S, Louie B, Seoane J, Zhou W, et al.
Science
. 2018 Oct;
362(6413).
PMID: 30361341
We present the genome-wide chromatin accessibility profiles of 410 tumor samples spanning 23 cancer types from The Cancer Genome Atlas (TCGA). We identify 562,709 transposase-accessible DNA elements that substantially extend...
9.
Shen H, Shih J, Hollern D, Wang L, Bowlby R, Tickoo S, et al.
Cell Rep
. 2018 Jun;
23(11):3392-3406.
PMID: 29898407
We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited high aneuploidy and a paucity of somatic mutations....
10.
Blum A, Wang P, Zenklusen J
Cell
. 2018 Apr;
173(2):530.
PMID: 29625059
This SnapShot provides a list of the tumor types characterized by The Cancer Genome Atlas (TCGA) program. Key findings shown are the most relevant discoveries described in each marker paper...